Complications in pregnant women with sickle cell disease

K Smith-Whitley - Hematology 2014, the American Society of …, 2019 - ashpublications.org
Pregnancy in women with sickle cell disease (SCD) is associated with increased maternal
and fetal morbidity and mortality. Outcomes vary widely owing to methodological limitations …

Hydroxyurea treatment for sickle cell anemia during pregnancy and lactation: current evidence and knowledge gaps

M Dong, RE Ware, A Dallmann… - … : The Journal of Human …, 2023 - Wiley Online Library
Sickle cell anemia (SCA) is a life‐threatening genetic condition contributing to high‐risk
pregnancies affecting both the mother and fetus. With improved management of children …

Sevoflurane relieves hepatic ischemia–reperfusion injury by inhibiting the expression of Grp78

D Liu, X Jin, C Zhang, Y Shang - Bioscience Reports, 2018 - portlandpress.com
Purpose: This article aimed to study the role of sevoflurane pre-conditioning in hepatic
ischemia–reperfusion and its potential mechanism. Methods: Rat liver ischemia–reperfusion …

Epigenetic analysis in placentas from sickle cell disease patients reveals a hypermethylation profile

GP Gil, G Ananina, M Maschietto, SCS Lima… - Plos one, 2022 - journals.plos.org
Pregnancy in Sickle Cell Disease (SCD) women is associated to increased risk of clinical
and obstetrical complications. Placentas from SCD pregnancies can present increased …

Hemoglobin Genotypes Modulate Inflammatory Response to Plasmodium Infection

KO Harp, F Botchway, Y Dei-Adomakoh… - Frontiers in …, 2020 - frontiersin.org
In 2018, 228 million cases and 405,000 malaria-associated deaths were reported worldwide
with a majority being in Africa. A wide range of factors, including parasitemia, host immunity …

Circ_0007611 stimulates IL-1 receptor accessory protein to inhibit trophoblast cell proliferation and induce cell apoptosis

H Xing, Q Ding, H Lu, Q Li - Biology of Reproduction, 2022 - academic.oup.com
Preeclampsia (PE) is a common pregnancy disorder, and mounting evidence has revealed
that circular RNA participates in PE development. However, the detailed molecular …

[HTML][HTML] Main complications during pregnancy and recommendations for adequate antenatal care in sickle cell disease: a literature review

CO Figueira, FG Surita, K Fertrin… - Revista Brasileira de …, 2022 - SciELO Brasil
Sickle cell disease (SCD) is the most common monogenic disease worldwide, with a
variable prevalence in each continent. A single nucleotide substitution leads to an amino …

Impact of vitamin B12 on the reproductive health of women with sickle cell disease: a narrative review

T Agbalalah, FO Robert… - Reproduction and Fertility, 2023 - raf.bioscientifica.com
Sickle cell disease (SCD) poses an increased risk of infertility, pregnancy complications and
maternal and perinatal mortality among women of reproductive age. This risk is particularly …

Circ_0003314 Combines with the miR-26b-5p/IL1RAP Axis to Inhibit HTR-8/SVneo Cell Proliferation, Migration, Invasion and Tube Formation and Promote Apoptosis

X Li, L Li, L Ruan - Applied Biochemistry and Biotechnology, 2024 - Springer
Preeclampsia (PE) is a pregnancy-related syndrome that can lead to a variety of
pathophysiological processes, such as impaired implantation. The pathogenesis of PE …

Гемоглобин: модификации, кристаллизация, полимеризация (обзор)

ВА Сергунова, ЕА Манченко… - Общая …, 2016 - cyberleninka.ru
Цель обзора: привести наиболее значимые модификации и превращения молекулы
гемоглобина, которые могут быть использованы для выработки стратегии …