Loss of auditory sensory hair cells (HCs) is the most common cause of hearing loss. This
review addresses the signaling pathways that are involved in the programmed and necrotic …

Patients that receive radiotherapy are at risk of late sensorineural hearing loss when the
inner ear is included within the radiation field. Preclinical and human temporal bone studies …

Background Sensorineural hearing loss (SNHL) is one of the major long term side effects
from radiation therapy (RT) in nasopharyngeal cancer (NPC) patients. This study aims to …

Abstract Background Glutathione S‐transferase (GST) enzymes are involved in detoxifying
chemotherapy and clearing reactive oxygen species formed by radiation. We explored the …

Radiation and chemotherapy are frequently used in the treatment of head and neck
malignancies. Ototoxicity is a common adverse effect of these treatment modalities. This …

Simple Summary Sensorineural hearing loss is a common late complication among
nasopharyngeal cancer survivors, primarily due to the close proximity of the auditory …

Introduction: Tetramethylpyrazine (TMP) is a chemical compound, which has been shown to
possess numerous biological features such as anticoagulation, inhibition of platelet …

Background: Most previous studies are separate dosimetric analyses of conductive or
sensorineural hearing loss, and they are not conducive to a comprehensive assessment of …

Objective There is currently no treatment available to prevent radiation-induced
sensorineural hearing loss. Metformin has antineoplastic effects and is able to regulate the …

Background Tinnitus can occur during and after treatment for childhood cancer. Studies on
the occurrence of, and risk factors for tinnitus during and after childhood cancer treatment …