The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates.
While their antibacterial activity toward bacterial cells was the original focus for research …

Cancer stem cells (CSCs) are the key factor in determining cancer recurrence, metastasis,
chemoresistance and patient prognosis in hepatocellular carcinoma (HCC). The role of miR …

Head and neck squamous cell carcinoma (HNSCC) is the most common type of head and
neck tumor. It is a high incidence malignant tumor associated with a low survival rate and …

Antimicrobial peptides (AMPs) are natural biopolymers in the host defense system. AMPs
display multiple functions against bacterial, fungal, and viral infection, as well as anticancer …

Representing severe morbidity and mortality globally, respiratory infections associated with
chronic respiratory diseases, including complicated pneumonia, asthma, interstitial lung …

Fibrosis exists in almost all organs/tissues of the human body, plays an important role in the
occurrence and development of diseases and is also a hallmark of the aging process …

Toll-like receptors (TLRs) play an important role between innate and adaptive immunity as
one of the pattern recognition receptors (PRRs). Both immune cells and tumor cells express …

Abstract Cathelicidin hCAP18/LL-37 can resist infection from various pathogens and is an
essential component of the human immune system. Accumulating evidence has indicated …

In many organisms, antimicrobial peptides (AMPs) display wide activities in innate host
defense against microbial pathogens. Mammalian AMPs include the cathelicidin and …