The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …

In light of the high incidence and mortality rates of cancer, early and accurate diagnosis is an
important priority for assigning optimal treatment for each individual with suspected illness …

Context.—The need for appropriate specimen use for ancillary testing has become more
commonplace in the practice of pathology. This, coupled with improvements in technology …

Tumor DNA contains specific somatic alterations that are crucial for the diagnosis and
treatment of cancer. Due to the spatial and temporal intra-tumor heterogeneity, multi …

Checkpoint inhibitor therapy constitutes a promising cancer treatment strategy that targets
the immune checkpoints to re-activate silenced T cell cytotoxicity. In recent pivotal trials …

Lung cancer is indeed a major cause of cancer‐related deaths worldwide. The development
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …

Small-cell lung cancer (SCLC), accounting for 10–20% of all lung tumors, represents the
most aggressive high-grade neuroendocrine carcinoma. Most patients are diagnosed with …

Asbestos is a naturally occurring mineral consisting of extremely fine fibres that can become
trapped in the lungs after inhalation. Occupational and environmental exposures to asbestos …

This manuscript addresses the role of O 6-methylguanine-DNA methyltransferase (MGMT)
as a biomarker in the oncogenesis of cancer and the opportunity of turning this gene into a …

小细胞肺癌（ small cell lung cancer, SCLC） 是一种高度恶性肿瘤， 初始治疗对放化疗均较敏感
， 缓解率高， 但治疗后易发生耐药并复发。 虽然近年来肺癌的治疗发生了翻天覆地的变化 …