Peptides are at the cutting edge of contemporary research for new potent, selective, and
safe therapeutical agents. Their rise has reshaped the pharmaceutical landscape, providing …

Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …

Atherosclerosis is a leading cause of cardiovascular disease worldwide, and
hypercholesterolemia is a major risk factor. Preventive treatments mainly focus on the …

The use of biologics (peptide and protein based drugs) has increased significantly over the
past few decades. However, their development has been limited by their short half-life …

Cardiovascular disease (CVD) remains a leading cause of mortality and morbidity
worldwide. Numerous therapies are currently under investigation to improve pathological …

Low plasma levels of high-density lipoprotein (HDL) cholesterol are associated with
increased risks of coronary heart disease. HDL mediates cholesterol efflux from …

Alzheimer's disease (AD) represents a progressive amyloidogenic disorder whose
advancement is widely recognized to be connected to amyloid-β peptides and Tau …

Dengue is a mosquito-borne infectious disease that is highly endemic in tropical and
subtropical countries. Symptomatic patients can rapidly progress to severe conditions of …

Apolipoprotein AI (apoA-I) mediates reverse cholesterol transport (RCT) out of cells. In
addition to its important role in the RTC, apoA-I also possesses anti-inflammatory and …

Lipoproteins are endogenous nanoparticles which are the major transporter of fats and
cholesterol in the human body. They play a key role in the regulatory mechanisms of …