The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …

Elongator is a 6 subunit protein complex highly conserved in eukaryotes. The role of this
complex has been controversial as the pleiotropic phenotypes of Elongator mutants have …

Post-transcriptional modification of nucleosides in transfer RNAs (tRNAs) is an important
process for accurate and efficient translation of the genetic information during protein …

The kingdoms of life share many small molecule cofactors and coenzymes. Molybdenum
cofactor (Moco) is synthesized by many archaea, bacteria, and eukaryotes, and is essential …

We studied two pathways that involve the transfer of persulfide sulfur in humans,
molybdenum cofactor biosynthesis and tRNA thiolation. Investigations using human cells …

Modification of wobble uridines of many eukaryotic tRNA s requires the Elongator complex,
a highly conserved six‐subunit eukaryotic protein assembly, as well as the Killer toxin …

The recent discovery of protein modification by SAMPs, ubiquitin‐like (Ubl) proteins from the
archaeon Haloferax volcanii, prompted a comprehensive comparative‐genomic analysis of …

Within shared ecological niches, secretion of lethal protein toxins by microorganisms is a
common strategy to ensure positive selection and survival of the toxin producing killer …

Within shared ecological niches, secretion of lethal toxins by microorganisms often ensures
survival of the toxin producing killer strains amongst other microbial competitors. Not …