Brugada syndrome

AD Krahn, ER Behr, R Hamilton, V Probst… - Clinical …, 2022 - jacc.org
Brugada syndrome (BrS) is an “inherited” condition characterized by predisposition to
syncope and cardiac arrest, predominantly during sleep. The prevalence is∼ 1: 2,000, and …

Sudden cardiac death: an update

J Isbister, C Semsarian - Internal medicine journal, 2019 - Wiley Online Library
Sudden cardiac death (SCD) is a devastating and all too common result of both acquired
and genetic heart diseases. The profound sadness endured by families is compounded by …

Subepicardial cardiomyopathy: a disease underlying J-wave syndromes and idiopathic ventricular fibrillation

C Miles, BJ Boukens, C Scrocco, AAM Wilde… - Circulation, 2023 - Am Heart Assoc
Brugada syndrome (BrS), early repolarization syndrome (ERS), and idiopathic ventricular
fibrillation (iVF) have long been considered primary electrical disorders associated with …

Electroanatomic and pathologic right ventricular outflow tract abnormalities in patients with Brugada syndrome

M Pieroni, P Notarstefano, A Oliva… - Journal of the American …, 2018 - jacc.org
Background: The prevalence and significance of structural abnormalities in Brugada
syndrome (BrS) are still largely debated. Objectives: The authors investigated the …

Biventricular myocardial fibrosis and sudden death in patients with Brugada syndrome

C Miles, A Asimaki, IC Ster, M Papadakis, B Gray… - Journal of the American …, 2021 - jacc.org
Background Electrophysiological, imaging, and pathological studies have reported the
presence of subtle structural abnormalities in hearts from patients with Brugada syndrome …

Morphological phenotype of right ventricular outflow tract is associated with cardiovascular outcomes and premature death

D Mao, C Li, D Zheng, K Jiang, Y He, Y Fang, Y Bai… - Scientific Reports, 2024 - nature.com
Morphology of right ventricular outflow tract (RVOT) is potentially related to cardiovascular
outcomes. However, this relationship still remains to be verified with direct evidence. We …

Structural heart alterations in Brugada syndrome: is it really a channelopathy? A systematic review

A Oliva, S Grassi, V Pinchi, F Cazzato, M Coll… - Journal of Clinical …, 2022 - mdpi.com
Brugada syndrome (BrS) is classified as an inherited cardiac channelopathy attributed to
dysfunctional ion channels and/or associated proteins in cardiomyocytes rather than to …

[HTML][HTML] New electromechanical substrate abnormalities in high-risk patients with Brugada syndrome

C Pappone, V Mecarocci, F Manguso, G Ciconte… - Heart Rhythm, 2020 - Elsevier
Background The relationship between the typical electrocardiographic pattern and
electromechanical abnormalities has never been systematically explored in Brugada …

[HTML][HTML] Longitudinal assessment of structural phenotype in Brugada syndrome using cardiac magnetic resonance imaging

JC Isbister, B Gray, S Offen, L Yeates, C Naoum… - Heart Rhythm O2, 2023 - Elsevier
Background Despite historically being considered a channelopathy, subtle structural
changes have been reported in Brugada syndrome (BrS) on histopathology and cardiac …

Worse prognosis in Brugada syndrome patients with arrhythmogenic cardiomyopathy features

E Scheirlynck, M Chivulescu, ØH Lie, A Motoc… - Clinical …, 2020 - jacc.org
Objectives This study aimed to assess the presence of echocardiographic and
electrocardiographic similarities in patients with Brugada syndrome (BrS) and …