Importance of the major histocompatibility complex (swine leukocyte antigen) in swine health and biomedical research

SE Hammer, CS Ho, A Ando… - Annual review of …, 2020 - annualreviews.org
In pigs, the major histocompatibility complex (MHC), or swine leukocyte antigen (SLA)
complex, maps to Sus scrofa chromosome 7. It consists of three regions, the class I and …

Global miRNA, lncRNA, and mRNA transcriptome profiling of endometrial epithelial cells reveals genes related to porcine reproductive failure caused by porcine …

K Zhang, L Ge, S Dong, Y Liu, D Wang, C Zhou… - Frontiers in …, 2019 - frontiersin.org
Porcine reproductive and respiratory syndrome virus (PRRSV) can cause respiratory
disease and reproductive failure in pregnant pigs. Previous transcriptome analyses in …

SLA-1 Genetic Diversity in Pigs: Extensive Analysis of Copy Number Variation, Heterozygosity, Expression, and Breed Specificity

MT Le, H Choi, H Lee, VCQ Le, B Ahn, CS Ho… - Scientific Reports, 2020 - nature.com
Swine leukocyte antigens play indispensable roles in immune responses by recognizing a
large number of foreign antigens and thus, their genetic diversity plays a critical role in their …

Swine leukocyte antigen diversity in Canadian specific pathogen-free Yorkshire and landrace pigs

C Gao, J Quan, X Jiang, C Li, X Lu, H Chen - Frontiers in Immunology, 2017 - frontiersin.org
The highly polymorphic swine major histocompatibility complex (MHC), termed swine
leukocyte antigen (SLA), is associated with different levels of immunologic responses to …

[HTML][HTML] Immunopeptidomics of Salmonella enterica Serovar Typhimurium-Infected Pig Macrophages Genotyped for Class II Molecules

C Celis-Giraldo, CF Suárez, W Agudelo, N Ibarrola… - Biology, 2024 - mdpi.com
Salmonellosis is a zoonotic infection that has a major impact on human health; consuming
contaminated pork products is the main source of such infection. Vaccination responses to …

Genetic Diversity and Sequence Conservation of Peptide-Binding Regions of MHC Class I Genes in Pig, Cattle, Chimpanzee, and Human

S Youk, M Kang, B Ahn, Y Koo, C Park - Genes, 2023 - mdpi.com
Comparative analyses of MHC gene diversity and evolution across different species could
offer valuable insights into the evolution of MHC genes. Intra-and inter-species sequence …

Genetic association between swine leukocyte antigen class II haplotypes and reproduction traits in microminipigs

A Ando, N Imaeda, T Matsubara, M Takasu… - Cells, 2019 - mdpi.com
The effects of swine leukocyte antigen (SLA) molecules on numerous production and
reproduction performance traits have been mainly reported as associations with specific …

A comparative analysis of SLA-DRB1 genetic diversity in Colombian (creoles and commercial line) and worldwide swine populations

CT Celis-Giraldo, MD Bohórquez, M Camargo… - Scientific Reports, 2021 - nature.com
Analysing pig class II mayor histocompatibility complex (MHC) molecules is mainly related to
antigen presentation. Identifying frequently-occurring alleles in pig populations is an …

Wild Boar (Sus scrofa)—Fascioloides magna Interaction from the Perspective of the MHC Genes

D Konjević, V Erman, M Bujanić, I Svetličić… - Pathogens, 2022 - mdpi.com
Fascioloidosis is a parasitic disease caused by a trematode Fascioloides magna. Since
major histocompatibility complex (MHC) genes play an important role in the immune …

Evolution of MHC class II SLA‐DRB1 locus in the Croatian wild boar (Sus scrofa) implies duplication and weak signals of positive selection

H Arbanasić, D Konjević, L Vranković… - Animal …, 2019 - Wiley Online Library
The wild boar is an ancestor of the domestic pig and an important game species with the
widest geographical range of all ungulates. Although a large amount of data are available …