Viral protein glycosylation represents a successful strategy employed by the parasite to take
advantage of host–cell machinery for modification of its own proteins. The resulting glycans …

Proteoglycosylation is the addition of monosaccharides or glycans to the protein peptide
chain. This is a common post-translational modification of proteins with a variety of biological …

The envelope glycoprotein GP of the ebolaviruses is essential for host cell entry and the
primary target of the host antibody response. GP is heavily glycosylated with up to 17 N …

The spike protein of SARS-CoV-2, the virus responsible for the global pandemic of COVID-
19, is an abundant, heavily glycosylated surface protein that plays a key role in receptor …

As the high pathogenic species of Filoviridae virus family, Orthoebolavirus zairense (EBOV)
shows frequent outbreaks in human in recently years since its first emerging in 1976 in …

Membrane proteins and lipids have the capacity to associate into lateral domains in cell
membranes through mutual or collective interactions. Lipid rafts are functional lateral …

Ebola virus glycoprotein (EBOV GP) is one of the most heavily O-glycosylated viral
glycoproteins, yet we still lack a fundamental understanding of the structure of its large O …

Abstract Infectious Hematopoietic Necrosis (IHN) is a viral disease that causes great
economic losses in salmonid fish farming industry. It is known that the N-glycosylation site …

Infection by the Ebola virus, a member of the Filoviridae family of RNA viruses, leads to
acute viral hemorrhagic fever. End-stage Ebola virus disease is characterized by a cytokine …

Ebola (EBOV) and Marburg virus (MARV) are highly pathogenic filoviruses that influence
cellular signaling according to their own needs. MARV has been shown to regulate the …