Casein kinase 2 (CK2): A possible therapeutic target in acute myeloid leukemia

Ø Bruserud, H Reikvam - Cancers, 2023 - mdpi.com
Simple Summary Acute myeloid leukemia (AML) is an aggressive blood cancer disease that
can only be cured by intensive anticancer treatment, and for several patients, allogeneic …

Non-homologous End-joining Genotype, mRNA Expression, and DNA Repair Capacity in Childhood Acute Lymphocytic Leukemia

CC Chen, WS Chang, JS Pei, CC Kuo… - Cancer Genomics & …, 2024 - cgp.iiarjournals.org
Abstract Background/Aim: The capacity for non-homologous end-joining (NHEJ) repair plays
a pivotal role in maintaining genome stability and in carcinogenesis. However, there is little …

DNA Repair Enzyme XRCC4 30 bp Indel Intron 3 Locus Significant Association with Predisposition of Cataract in Senility

S Kafeel, N Bizenjo, SS Shivji, A Keran… - Applied Biochemistry …, 2024 - Springer
Impaired DNA damage repair cascade can disrupt the lens transparency due to aging-
associated oxidative stress. The aim of study was to assess the association of 30 bp indel …

[HTML][HTML] KMT2A-rearranged acute lymphoblastic leukaemia

RS Kotecha, R Pieters, J Stutterheim - EJC Paediatric Oncology, 2024 - Elsevier
KMT2A-rearranged acute lymphoblastic leukaemia (ALL) represents a high-risk subtype of
childhood ALL. Historical treatment strategies have comprised of intensification with …

Deteksi variasi genetik gen xrcc4 intron 3 (rs28360071) pada pekerja radiasi medis di Indonesia

M Putri - repository.uinjkt.ac.id
Paparan radiasi pengion dapat menyebabkan kerusakan DNA tipe Double-Strand Break
(DSB). DSB dapat diperbaiki dengan jalur Non-Homologous End Joining (NHEJ). X-ray …