Kidney organoids: a pioneering model for kidney diseases

M Tekguc, RC Van Gaal, SGM Uzel, N Gupta… - Translational …, 2022 - Elsevier
The kidney is a vital organ that regulates the bodily fluid and electrolyte homeostasis via
tailored urinary excretion. Kidney injuries that cause severe or progressive chronic kidney …

A review of medicinal plants with renoprotective activity in diabetic nephropathy animal models

IMWA Putra, N Fakhrudin, A Nurrochmad, S Wahyuono - Life, 2023 - mdpi.com
Diabetic nephropathy (DN), also recognized as diabetic kidney disease, is a kidney
malfunction caused by diabetes mellitus. A possible contributing factor to the onset of DN is …

KIRREL promotes the proliferation of gastric cancer cells and angiogenesis through the PI3K/AKT/mTOR pathway

T Wang, S Chen, Z Wang, S Li, X Fei… - Journal of Cellular …, 2024 - Wiley Online Library
Anti‐angiogenesis is a promising therapeutic strategy for delaying tumour progression that
offers, new hope for gastric cancer targeted therapy. The purpose of this study was to …

Protective effect of compound K against podocyte injury in chronic kidney disease by maintaining mitochondrial homeostasis

F Huang, S Huang, K Sun, Y Chen, G Xie, J Bao… - Scientific Reports, 2025 - nature.com
Chronic kidney disease (CKD) stands as a formidable global health challenge, often
advancing to end-stage renal disease (ESRD) with devastating morbidity and mortality. At …

GDF-15 suppresses puromycin aminonucleoside-induced podocyte injury by reducing endoplasmic reticulum stress and glomerular inflammation

E von Rauchhaupt, M Klaus, A Ribeiro, M Honarpisheh… - Cells, 2024 - mdpi.com
GDF15, also known as MIC1, is a member of the TGF-beta superfamily. Previous studies
reported elevated serum levels of GDF15 in patients with kidney disorder, and its …

Using Drosophila Nephrocytes to Understand the Formation and Maintenance of the Podocyte Slit Diaphragm

J van de Leemput, P Wen, Z Han - Frontiers in Cell and …, 2022 - frontiersin.org
The podocyte slit diaphragm (SD) is an essential component of the glomerular filtration
barrier and its disruption is a common cause of proteinuria and many types of kidney …

Enhancing Renal Autophagy via Yangshen Paidu Decoction: AMPK/mTOR Pathway Modulation in Chronic Renal Failure Management

H Tang, Q Tao, Y Li, X Bai, D Lv, F Wang… - Letters in Drug …, 2024 - benthamdirect.com
Objective Chronic Renal Failure (CRF) refers to the gradual decline in renal function caused
by various chronic kidney diseases, eventually leading to end-stage renal failure. Yangshen …

[HTML][HTML] Renal protective effect of Isaria felina mycelium powder on diet and STZ-induced diabetes mice and the identification of major chemical constituents

Z HUANG, C Jingjing, Z Lili, C Lixia, Y Yuxin… - Chinese Journal of …, 2024 - Elsevier
Type 2 diabetes is a group of metabolic diseases mainly characterized by chronic
hyperglycemia. Diabetic kidney disease is the most common microvascular complication of …

Genetische Faktoren bei Muskelverletzungen im Sport

F Pfab, J Sieland, C Haser, W Banzer, T Kocher - Die Orthopädie, 2023 - Springer
Zusammenfassung Hintergrund Das menschliche Genom ist der vollständige Satz
genetischer Anweisungen, die in der DNA eines Individuums codiert sind. Die Genetik kann …

[图书][B] Developing an experimental murine autoimmune model of nephrotic syndrome driven by a podocytopathic humoral response

MA Ste-Croix - 2023 - search.proquest.com
Idiopathic nephrotic syndrome (INS) is a rare pediatric disease characterized by severe
proteinuria of unknown etiology, with most cases presenting as Minimal Change Disease …