Alzheimer's disease and its treatment by different approaches: A review

S Srivastava, R Ahmad, SK Khare - European Journal of Medicinal …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

NADPH oxidase in brain injury and neurodegenerative disorders

MW Ma, J Wang, Q Zhang, R Wang… - Molecular …, 2017 - Springer
Oxidative stress is a common denominator in the pathology of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral …

Alzheimer's disease, dementia, and stem cell therapy

T Duncan, M Valenzuela - Stem cell research & therapy, 2017 - Springer
Alzheimer's disease (AD) represents arguably the most significant social, economic, and
medical crisis of our time. Characterized by progressive neurodegenerative pathology, AD is …

[HTML][HTML] Stem cell therapy for Alzheimer's disease

XY Liu, LP Yang, L Zhao - World journal of stem cells, 2020 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and cognitive impairment. It is caused by synaptic failure and excessive …

High-throughput screening platforms in the discovery of novel drugs for neurodegenerative diseases

H Aldewachi, RN Al-Zidan, MT Conner, MM Salman - Bioengineering, 2021 - mdpi.com
Neurodegenerative diseases (NDDs) are incurable and debilitating conditions that result in
progressive degeneration and/or death of nerve cells in the central nervous system (CNS) …

Physical exercise induces hippocampal neurogenesis and prevents cognitive decline

CL Ma, XT Ma, JJ Wang, H Liu, YF Chen… - Behavioural brain …, 2017 - Elsevier
Accumulating evidence from animal and human research indicate that adult hippocampal
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …

Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development

BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

Neural stem cell therapy for neurodegenerative disorders: the role of neurotrophic support

SE Marsh, M Blurton-Jones - Neurochemistry international, 2017 - Elsevier
Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and
Huntington's disease currently affect tens of millions of people worldwide. Unfortunately, as …

Cell therapy for neurological disorders

SP Svendsen, CN Svendsen - Nature Medicine, 2024 - nature.com
Cell therapies for neurological disorders are entering the clinic and present unique
challenges and opportunities compared with conventional medicines. They have the …

Neurodegeneration and neuro-regeneration—Alzheimer's disease and stem cell therapy

V Vasic, K Barth, MHH Schmidt - International journal of molecular …, 2019 - mdpi.com
Aging causes many changes in the human body, and is a high risk for various diseases.
Dementia, a common age-related disease, is a clinical disorder triggered by …