Bioactive peptides from food fermentation: A comprehensive review of their sources, bioactivities, applications, and future development

KF Chai, AYH Voo, WN Chen - Comprehensive Reviews in …, 2020 - Wiley Online Library
Bioactive peptides (BPs) are specific protein fragments that exert various beneficial effects
on human bodies and ultimately influence health, depending on their structural properties …

Understanding dietary intervention-mediated epigenetic modifications in metabolic diseases

S Asif, NM Morrow, EE Mulvihill, KH Kim - Frontiers in Genetics, 2020 - frontiersin.org
The global prevalence of metabolic disorders, such as obesity, diabetes and fatty liver
disease, is dramatically increasing. Both genetic and environmental factors are well-known …

Cacao extract enriched in polyphenols prevents endocrine-metabolic disturbances in a rat model of prediabetes triggered by a sucrose rich diet

MC Castro, H Villagarcia, A Nazar, LG Arbeláez… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Cocoa extracts rich in polyphenols are used as potential
agent for treating diabetes. Cocoa polyphenols have been proved to ameliorate important …

Alpha-lipoic acid and its protective role in fructose induced endocrine-metabolic disturbances

MC Castro, HG Villagarcía, ML Massa, F Francini - Food & function, 2019 - pubs.rsc.org
In recent decades a worldwide increase has been reported in the consumption of unhealthy
high calorie diets associated with marked changes in meal nutrient composition, such as a …

Chronological appearance of endocrine and metabolic dysfunctions induced by an unhealthy diet in rats

MC Castro, HG Villagarcía, CL Román, B Maiztegui… - Medicina, 2021 - mdpi.com
Background and Objectives: The work was aimed to determine the chronological sequence
of events triggered by a fructose-rich diet (FRD)(10% w/v in the drinking water) in normal …

[HTML][HTML] Mitochondrial uncoupling protein 2: a central player in pancreatic disease pathophysiology

K Wang, L Zhang, B Deng, K Zhao, C Chen… - Molecular …, 2024 - pmc.ncbi.nlm.nih.gov
Pancreatic diseases pose considerable health challenges due to their complex etiology and
limited therapeutic options. Mitochondrial uncoupling protein 2 (UCP2), highly expressed in …

Structural modifications of INGAP-PP present in HTD4010 peptide potentiate its effect on rat islet gene expression and insulin secretion.

M Algañarás, CL Román, JJ Gagliardino, B Maiztegui… - Peptides, 2024 - Elsevier
Abstract Type 2 diabetes (T2D) is characterized by peripheral insulin resistance and altered
insulin secretion due to a progressive loss of β-cell mass and function. Today, most …

Búsqueda de marcadores predictivos de diabetes y prediabetes a través de la identificación de genes diferencialmente metilados en islotes y leucocitos de ratas …

L Ahrtz - 2024 - sedici.unlp.edu.ar
En esta tesis se valida el modelo por el cual ratas alimentadas con una DRF por 21 días
generan un desbalance metabólico similar a la PD humana, con presencia de TGA …

[PDF][PDF] Rol del estrés del retículo endoplasmático y de la respuesta inflamatoria en la disfunción de las células β pancreáticas inducida por dieta rica en fructosa

F Vásquez, S Catherine - med.unlp.edu.ar
La administración de una dieta rica en fructosa (DRF) a ratas normales induce cambios
endocrino-metabólicos similares a los de la prediabetes (PD) humana, donde el estrés del …

Efectos del tratamiento antioxidante en la activación del eje hipotálamo-hipófiso-adrenal inducida por el consumo de dietas ricas en sacarosa

ME Mercau, JS Calanni, ML Aranda, RE Rosenstein… - 2020 - ri.conicet.gov.ar
Introducción: dados los efectos pleiotrópicos de los glucocorticoides (GCs) sobre el
metabolismo, los niveles excesivos y sostenidos de GCs circulantes tienen efectos …