D St Johnston - Nature reviews genetics, 2002 - nature.com
The success of Drosophila melanogaster as a model organism is largely due to the power of forward genetic screens to identify the genes that are involved in a biological process …
LT Reiter, L Potocki, S Chien, M Gribskov… - Genome …, 2001 - genome.cshlp.org
We performed a systematic BLAST analysis of 929 human disease gene entries associated with at least one mutant allele in the Online Mendelian Inheritance in Man (OMIM) database …
The social amoebae are exceptional in their ability to alternate between unicellular and multicellular forms. Here we describe the genome of the best-studied member of this group …
E Bier - Nature Reviews Genetics, 2005 - nature.com
Drosophila melanogaster is emerging as one of the most effective tools for analyzing the function of human disease genes, including those responsible for developmental and …
K Prüßing, A Voigt, JB Schulz - Molecular neurodegeneration, 2013 - Springer
Drosophila melanogaster provides an important resource for in vivo modifier screens of neurodegenerative diseases. To study the underlying pathogenesis of Alzheimer's disease …
Insect Biodiversity: Science and Society brings together leading scientific experts to assess the impact insects have on humankind and the earth's fragile ecosystems. It examines why …
Y Apidianakis, LG Rahme - Disease models & mechanisms, 2011 - journals.biologists.com
Recent findings concerning Drosophila melanogaster intestinal pathology suggest that this model is well suited for the study of intestinal stem cell physiology during aging, stress and …
Diptera are major contributors to the maintenance of plant diversity through their participation in pollination systems and networks. Diptera are rich in species with specific …
JK Inlow, LL Restifo - Genetics, 2004 - academic.oup.com
Abstract Affecting 1-3% of the population, mental retardation (MR) poses significant challenges for clinicians and scientists. Understanding the biology of MR is complicated by …