The power of imaging to understand extracellular vesicle biology in vivo

FJ Verweij, L Balaj, CM Boulanger, DRF Carter… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every
cell type. EVs have diverse biological activities, ranging from roles in development and …

The art and design of genetic screens: Drosophila melanogaster

D St Johnston - Nature reviews genetics, 2002 - nature.com
The success of Drosophila melanogaster as a model organism is largely due to the power of
forward genetic screens to identify the genes that are involved in a biological process …

A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster

LT Reiter, L Potocki, S Chien, M Gribskov… - Genome …, 2001 - genome.cshlp.org
We performed a systematic BLAST analysis of 929 human disease gene entries associated
with at least one mutant allele in the Online Mendelian Inheritance in Man (OMIM) database …

The genome of the social amoeba Dictyostelium discoideum

L Eichinger, JA Pachebat, G Glöckner, MA Rajandream… - Nature, 2005 - nature.com
The social amoebae are exceptional in their ability to alternate between unicellular and
multicellular forms. Here we describe the genome of the best-studied member of this group …

Drosophila, the golden bug, emerges as a tool for human genetics

E Bier - Nature Reviews Genetics, 2005 - nature.com
Drosophila melanogaster is emerging as one of the most effective tools for analyzing the
function of human disease genes, including those responsible for developmental and …

Drosophila melanogaster as a model organism for Alzheimer's disease

K Prüßing, A Voigt, JB Schulz - Molecular neurodegeneration, 2013 - Springer
Drosophila melanogaster provides an important resource for in vivo modifier screens of
neurodegenerative diseases. To study the underlying pathogenesis of Alzheimer's disease …

[图书][B] Insect biodiversity: science and society

RG Foottit, PH Adler - 2009 - books.google.com
Insect Biodiversity: Science and Society brings together leading scientific experts to assess
the impact insects have on humankind and the earth's fragile ecosystems. It examines why …

Drosophila melanogaster as a model for human intestinal infection and pathology

Y Apidianakis, LG Rahme - Disease models & mechanisms, 2011 - journals.biologists.com
Recent findings concerning Drosophila melanogaster intestinal pathology suggest that this
model is well suited for the study of intestinal stem cell physiology during aging, stress and …

Biodiversity of diptera

GW Courtney, T Pape, JH Skevington… - … : science and society, 2017 - Wiley Online Library
Diptera are major contributors to the maintenance of plant diversity through their
participation in pollination systems and networks. Diptera are rich in species with specific …

Molecular and comparative genetics of mental retardation

JK Inlow, LL Restifo - Genetics, 2004 - academic.oup.com
Abstract Affecting 1-3% of the population, mental retardation (MR) poses significant
challenges for clinicians and scientists. Understanding the biology of MR is complicated by …