Cholera remains a major global public health problem that is primarily linked to insufficient
access to safe water and proper sanitation. Oral Cholera Vaccine (OCV) has been …

Background Cholera is a cause of acute watery diarrhoea which can cause dehydration and
death if not adequately treated. It usually occurs in epidemics, and is associated with poverty …

Serum responses to oral cholera vaccines were assessed in three paediatric vaccine trials,
two in León, Nicaragua and one in Stockholm, Sweden. A calibrated anti-cholera toxin B …

With more than 100,000 cases estimated each year, Bangladesh is one of the countries with
the highest number of people at risk for cholera. Moreover, Bangladesh is formulating a …

Vibrio cholerae O1 can cause diarrheal disease that may be life-threatening without
treatment. Natural infection results in long-lasting protective immunity, but the role of T cells …

Background Injected cholera vaccines are rarely used today, although they may have some
benefit. It is valuable to summarize the evidence for effectiveness of injected cholera …

This study tests whether the effect of a vaccine trial varies in space and why. Analytical z-
score maps identify unusually high-and low-efficacy values in a trial area. Relationships …

Background Young children are one of the most vulnerable groups who may be infected
with cholera. The following literature review of the efficacy of the currently available cholera …

This paper develops theory and methods for vaccine trials that utilize spatial and
environmental information. Satellite imagery is used to identify whether households are …

Most disease in tropical and subtropical countries either has an infective basis or is a
manifestation of the infection-malnutrition cycle. Many of these diseases, such as …