Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling …

Abstract γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter released at
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …

The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …

Abstract Monoamine oxidase-B (MAO-B) inhibitors are commonly used for the symptomatic
treatment of Parkinson's disease (PD). MAO-B inhibitor monotherapy has been shown to be …

Purpose: Low level laser therapy (LLLT) in the visible to near infrared spectral band (390–
1100 nm) is absorption of laser light at the electronic level, without generation of heat. It may …

Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric
diseases, and that glial cells participate in synapse formation, development, and plasticity …

Monoamine oxidase (MAO) is believed to mediate the degradation of monoamine
neurotransmitters, including dopamine, in the brain. Between the two types of MAO, MAO-B …

The clinical definition of neurodegenerative diseases is based on symptoms that reflect
terminal damage of specific brain regions. This is misleading as it tells little about the initial …

Sensory discrimination is essential for survival. However, how sensory information is finely
controlled in the brain is not well defined. Here, we show that astrocytes control tactile acuity …

Classically, the loss of vulnerable neuronal populations in neurodegenerative diseases was
considered to be the consequence of cell autonomous degeneration of neurons. However …