RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

The protein menin is encoded by the MEN1 gene, which is mutated in patients with multiple
endocrine neoplasia type 1 (MEN1) syndrome. Although menin acts as a tumor suppressor …

The mitochondrial tumor suppressor 1 (MTUS1) gene acts as a crucial tumor suppressor by
inhibiting growth and proliferation of eukaryotic cells including tumor cell lines. Down …

During chronic liver disease, tissue remodeling leads to dramatic changes and
accumulation of matrix components. Matrix metalloproteases and their inhibitors have been …

Posttranscriptional regulation of gene expression of mRNAs containing adenine‐uridine rich
elements (AREs) in their 3′ untranslated regions is mediated by a number of different …

Menin is an enigmatic protein that displays unique ability to either suppress or promote
tumorigenesis in a context-dependent manner. The role for Menin to promote oncogenic …

Background Breast cancer is a multifactorial disease which involves number of molecular
factors that are critically involved in proliferation of breast cancer cells. MEN1 gene that is …

Menin is a scaffold protein encoded by the multiple endocrine neoplasia type 1 (MEN1)
gene in humans, and it interacts with a variety of transcriptional proteins to control active or …

Abstract Mixed lineage leukemia 1 (MLL1), a histone H3 lysine 4 (H3K4) methyltransferase,
exerts its enzymatic activity by interacting with menin and other proteins. It is unclear …

Background & Aims The development and progression of non-alcoholic fatty liver disease
are associated with aging, obesity, and type 2 diabetes. Understanding the precise …