Molecular transducers of physical activity consortium (MoTrPAC): mapping the dynamic responses to exercise
Exercise provides a robust physiological stimulus that evokes cross-talk among multiple
tissues that when repeated regularly (ie, training) improves physiological capacity, benefits …
tissues that when repeated regularly (ie, training) improves physiological capacity, benefits …
Integrative omics approaches for biosynthetic pathway discovery in plants
Covering: up to 2022 With the emergence of large amounts of omics data, computational
approaches for the identification of plant natural product biosynthetic pathways and their …
approaches for the identification of plant natural product biosynthetic pathways and their …
A transcription factor hierarchy defines an environmental stress response network
INTRODUCTION Transcription factors (TFs) are often studied one by one or in clusters of a
few related factors. However, the integration and networks of transcriptional changes to …
few related factors. However, the integration and networks of transcriptional changes to …
Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation
Cardiac differentiation of human pluripotent stem cells (hPSCs) requires orchestration of
dynamic gene regulatory networks during stepwise fate transitions but often generates …
dynamic gene regulatory networks during stepwise fate transitions but often generates …
Using neural networks for reducing the dimensions of single-cell RNA-Seq data
While only recently developed, the ability to profile expression data in single cells (scRNA-
Seq) has already led to several important studies and findings. However, this technology …
Seq) has already led to several important studies and findings. However, this technology …
Deep learning for inferring gene relationships from single-cell expression data
Y Yuan, Z Bar-Joseph - Proceedings of the National …, 2019 - National Acad Sciences
Several methods were developed to mine gene–gene relationships from expression data.
Examples include correlation and mutual information methods for coexpression analysis …
Examples include correlation and mutual information methods for coexpression analysis …
50 years of Arabidopsis research: highlights and future directions
The year 2014 marked the 25th International Conference on Arabidopsis Research. In the
50 yr since the first International Conference on Arabidopsis Research, held in 1965 in …
50 yr since the first International Conference on Arabidopsis Research, held in 1965 in …
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
Dynamic reprogramming of gene regulatory networks (GRNs) enables organisms to rapidly
respond to environmental perturbation. However, the underlying transient interactions …
respond to environmental perturbation. However, the underlying transient interactions …
Use cases, best practice and reporting standards for metabolomics in regulatory toxicology
MR Viant, TMD Ebbels, RD Beger, DR Ekman… - Nature …, 2019 - nature.com
Metabolomics is a widely used technology in academic research, yet its application to
regulatory science has been limited. The most commonly cited barrier to its translation is …
regulatory science has been limited. The most commonly cited barrier to its translation is …
Extensive transcriptomic and epigenomic remodelling occurs during Arabidopsis thaliana germination
Background Seed germination involves progression from complete metabolic dormancy to a
highly active, growing seedling. Many factors regulate germination and these interact …
highly active, growing seedling. Many factors regulate germination and these interact …