Human organ‐specific 3D cancer models produced by the stromal self‐assembly method of tissue engineering for the study of solid tumors

V Roy, B Magne, M Vaillancourt-Audet… - BioMed Research …, 2020 - Wiley Online Library
Cancer research has considerably progressed with the improvement of in vitro study
models, helping to understand the key role of the tumor microenvironment in cancer …

Tissue engineering for gastrointestinal and genitourinary tracts

E Elia, D Brownell, S Chabaud, S Bolduc - International Journal of …, 2022 - mdpi.com
The gastrointestinal and genitourinary tracts share several similarities. Primarily, these
tissues are composed of hollow structures lined by an epithelium through which materials …

Moyamoya Disease Susceptibility Gene RNF213 Regulates Endothelial Barrier Function

V Roy, JP Ross, R Pépin, S Cortez Ghio, A Brodeur… - Stroke, 2022 - Am Heart Assoc
Background: Variants in the ring finger protein 213 (RNF213) gene are known to be
associated with increased predisposition to cerebrovascular diseases development …

Gelatin/sodium alginate hydrogel-coated decellularized porcine coronary artery to construct bilayer tissue engineered blood vessels

J Du, X Hu, Y Su, T Wei, Z Jiao, T Liu, H Wang… - International Journal of …, 2022 - Elsevier
Cardiovascular diseases and vascular trauma can be commonly found in the population.
Scholars worldwide hope to develop small-diameter vascular grafts that can replace …

RNF213 loss-of-function promotes angiogenesis of cerebral microvascular endothelial cells in a cellular state dependent manner

V Roy, A Brodeur, L Touzel Deschênes, N Dupré… - Cells, 2022 - mdpi.com
Enhanced and aberrant angiogenesis is one of the main features of Moyamoya disease
(MMD) pathogenesis. The ring finger protein 213 (RNF213) and the variant p. R4810K have …

Genitourinary tissue engineering: Reconstruction and research models

C Caneparo, D Brownell, S Chabaud, S Bolduc - Bioengineering, 2021 - mdpi.com
Tissue engineering is an emerging field of research that initially aimed to produce 3D
tissues to bypass the lack of adequate tissues for the repair or replacement of deficient …

Reconstruction of vascular and urologic tubular grafts by tissue engineering

C Caneparo, S Chabaud, S Bolduc - Processes, 2021 - mdpi.com
Tissue engineering is one of the most promising scientific breakthroughs of the late 20th
century. Its objective is to produce in vitro tissues or organs to repair and replace damaged …

The Human Neonatal Skin Fibroblast, an Available Cell Source for Tissue Production and Transplantation, Exhibits Low Risk of Immunogenicity In Vitro

B Magne, K Ferland, É Savard, MA Barbier… - International Journal of …, 2024 - mdpi.com
The immunogenicity of allogeneic skin fibroblasts in transplantation has been controversial.
Whether this controversy comes from a natural heterogeneity among fibroblast subsets or …

Spherical rotary cell seeding system for production of small-caliber tissue-engineered blood vessels with complex geometry

A Brodeur, A Winter, V Roy, L Touzel Deschênes… - Scientific Reports, 2023 - nature.com
Entirely biological human tissue-engineered blood vessels (TEBV) were previously
developed for clinical use. Tissue-engineered models have also proven to be valuable tools …

Incorporating regenerative medicine into rehabilitation programmes: a potential treatment for ankle sprain

QF Gan, CN Foo, PP Leong… - International Journal of …, 2021 - magonlinelibrary.com
Ankle sprain has a great effect on morbidity and complications of chronic diseases. Experts
have come to a consensus where ankle sprain can be managed by rest, ice, compression …