Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds

HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

Anticancer potential of quercetin: A comprehensive review

A Rauf, M Imran, IA Khan, M ur‐Rehman… - Phytotherapy …, 2018 - Wiley Online Library
Diet plays a key role to maintaining healthy life. Many natural products present in our diet,
such as flavonoids, can prevent the progression of cancer. Quercetin, a distinctive bioactive …

A review on anti-cancer properties of Quercetin in breast cancer

M Ezzati, B Yousefi, K Velaei, A Safa - Life sciences, 2020 - Elsevier
Breast cancer is one of the well-known malignant tumors among women. In spite of attempts
to classifying breast cancer according to its histological and molecular properties, it is almost …

A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells

P Biswas, D Dey, PK Biswas, TI Rahaman… - International journal of …, 2022 - mdpi.com
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …

Natural polyphenols for prevention and treatment of cancer

Y Zhou, J Zheng, Y Li, DP Xu, S Li, YM Chen, HB Li - Nutrients, 2016 - mdpi.com
There is much epidemiological evidence that a diet rich in fruits and vegetables could lower
the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols …

Natural small molecules in breast cancer treatment: understandings from a therapeutic viewpoint

MR Islam, F Islam, MH Nafady, M Akter, S Mitra, R Das… - Molecules, 2022 - mdpi.com
Breast cancer (BrCa) is the most common malignancy in women and the second most
significant cause of death from cancer. BrCa is one of the most challenging malignancies to …

[HTML][HTML] The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC)

R Farghadani, R Naidu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Breast cancer is a leadingcause of cancer-related deaths in women globally, with triple-
negative breast cancer (TNBC) being an aggressive subtype that lacks targeted therapies …

Quercetin remodels the tumor microenvironment to improve the permeation, retention, and antitumor effects of nanoparticles

K Hu, L Miao, TJ Goodwin, J Li, Q Liu, L Huang - ACS nano, 2017 - ACS Publications
Our previous work demonstrated that Wnt16 expression in cisplatin-damaged tumor-
associated fibroblasts is a key factor contributing to cisplatin resistance in malignancies …

Flavonoids and other polyphenols act as epigenetic modifiers in breast cancer

P Selvakumar, A Badgeley, P Murphy, H Anwar… - Nutrients, 2020 - mdpi.com
Breast cancer is a common cancer that occurs due to different epigenetic alterations and
genetic mutations. Various epidemiological studies have demonstrated an inverse …

Quercetin shows anti‐tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway

L Wu, J Li, T Liu, S Li, J Feng, Q Yu, J Zhang… - Cancer …, 2019 - Wiley Online Library
Objective Hepatocellular carcinima is one of the most common tumors in clinic and also one
of the leading causes of death from cancer worldwide. Quercetin shows significant effects on …