Hemorrhagic shock (HS) management is based on a timely, rapid, definitive source control
of bleeding/s and on blood loss replacement. Stopping the hemorrhage from progressing …

Background Management of the critically bleeding patient can be encountered in many
medical and surgical settings. Common for these patients is a high risk of dying from …

Objectives Sustained changes in resuscitation and transfusion management have been
observed since the turn of the millennium, along with an ongoing discussion of surgical …

METHODS Prospectively collected data from the Pragmatic Randomized Optimal Platelet
and Plasma Ratios trial were analyzed. Hemostasis was predefined as no intraoperative …

Hemorrhage is the most important contributing factor of acute-phase mortality in trauma
patients. Previously, traumatologists and investigators identified iatrogenic and resuscitation …

Trauma resuscitation should focus on early goal-directed therapy with use of viscoelastic
haemostatic assays while initially applying a ratio 1: 1: 1 driven transfusion therapy (with red …

BACKGROUND Often the clinician is faced with a diagnostic and therapeutic dilemma in
patients with concomitant traumatic brain injury (TBI) and hemorrhagic shock (HS), as rapid …

Introduction: Despite advances in the treatment of severely injured patients that have
resulted in overall improved outcomes, uncontrolled hemorrhage still represents the most …

Background People with thrombocytopenia often require a surgical procedure. A low platelet
count is a relative contraindication to surgery due to the risk of bleeding. Platelet …

Introduction Early physiological assessment of multiple injured patients is crucial for
decision making and has relied on personal experience of trauma experts. We have …