Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …

With the development of nanotechnology, nanoparticles (NPs) have shown broad prospects
as drug delivery vehicles. However, they exhibit certain limitations, including low …

Extracellular vesicles (EVs) are emerging as biomarkers by inheriting biomolecular
information from their parental cells. They are highly heterogeneous and can reflect the …

Exosomes are becoming the surrogates of their parental cells by inheriting cell surface and
inner molecular information, thereby emerging as biomarkers in diseases diagnosis and …

The RNA contained in exosomes plays a crucial role in information transfer between cells in
various life activities. The accurate detection of low-abundance exosome RNA (exRNA) is of …

The characterization of single extracellular vesicle (EV) has been an emerging tool for the
early detection of various diseases despite there being challenges regarding how to …

Objective To propose EV-derived mRNA as a potential diagnostic biomarker detecting the
presence of clear cell renal cell carcinoma (ccRCC). There is currently no kidney cancer …

Simple Summary Prostate cancer lacks non-invasive specific biomarkers for aggressive
disease. Urinary extracellular vesicles (uEV) could provide such markers; however, due to …

Abstract mRNA‐based molecular subtypes have implications for bladder cancer prognosis
and clinical benefit from certain therapies. Whether small extracellular vesicles (sEVs) can …

The application of circulating tumor cells (CTCs) in both clinical practice and research has
been continuously limited by the rare number of targets that can be found in a tube of …