COL1A1: a novel oncogenic gene and therapeutic target in malignancies

X Li, X Sun, C Kan, B Chen, N Qu, N Hou, Y Liu… - … -Research and Practice, 2022 - Elsevier
Collagen type I alpha 1 (COL1A1), a member of the collagen family, is involved in epithelial–
mesenchymal transition, which is closely linked to malignant tumorigenesis. COL1A1 is …

[HTML][HTML] Alteration of the esophageal microbiota in Barrett's esophagus and esophageal adenocarcinoma

J Lv, L Guo, JJ Liu, HP Zhao, J Zhang… - World journal of …, 2019 - ncbi.nlm.nih.gov
The incidence of esophageal adenocarcinoma (EAC) has increased in recent decades, and
its 5-year survival rate is less than 20%. As a well-established precursor, patients with …

Mitochondrial uncoupling proteins: subtle regulators of cellular redox signaling

P Ježek, B Holendová, KD Garlid… - Antioxidants & Redox …, 2018 - liebertpub.com
Significance: Mitochondria are the energetic, metabolic, redox, and information signaling
centers of the cell. Substrate pressure, mitochondrial network dynamics, and cristae …

Aptamer-conjugated nanoliposomes containing COL1A1 siRNA sensitize CRC cells to conventional chemotherapeutic drugs

H Manoochehri, A Jalali, H Tanzadehpanah… - Colloids and Surfaces B …, 2022 - Elsevier
COL1A1 is an important extracellular matrix component that is associated with poor
prognosis in cancers. In this study, As1411 aptamer-conjugated liposomes were used for …

COL1A1 is a prognostic biomarker and correlated with immune infiltrates in lung cancer

Q Geng, Z Shen, L Li, J Zhao - PeerJ, 2021 - peerj.com
Objective Lung cancer (LC) is one of the top ten malignant tumors and the first leading
cause of cancer-related death among both men and women worldwide. It is imperative to …

UCP 2 gene polymorphisms in obesity and diabetes, and the role of UCP 2 in cancer

J Li, R Jiang, X Cong, Y Zhao - FEBS letters, 2019 - Wiley Online Library
Mitochondria are the primary sites for ATP synthesis and free radical generation in
organisms. Abnormal mitochondrial metabolism contributes to many diseases, including …

System biology analysis to develop diagnostic biomarkers, monitoring pathological indexes, and novel therapeutic approaches for immune targeting based on maggot …

E Kaviani, F Hajibabaie, N Abedpoor, K Safavi… - Environmental …, 2023 - Elsevier
Early diagnosis and prognosis are prerequisites for mitigating mortality in gastric cancer
(GaCa). Identifying some causative or sensitive elements (coding RNA (cRNA)-non-cRNAs …

[HTML][HTML] Collagen type 1 alpha 1 chain is a novel predictive biomarker of poor progression-free survival and chemoresistance in metastatic lung cancer

L Hou, T Lin, Y Wang, B Liu, M Wang - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Background: Collagen type 1 alpha 1 chain (COL1A1) is an extracellular matrix protein
comprising two alpha 1 chains and one alpha 2 chain. Our previous study identified that …

Molecular pathways and key genes associated with breast width and protein content in white striping and wooden breast chicken pectoral muscle

M Bordini, F Soglia, R Davoli, M Zappaterra… - Frontiers in …, 2022 - frontiersin.org
Growth-related abnormalities affecting modern chickens, known as White Striping (WS) and
Wooden Breast (WB), have been deeply investigated in the last decade. Nevertheless, their …

LncRNA LINC00511 promotes COL1A1-mediated proliferation and metastasis by sponging miR-126-5p/miR-218-5p in lung adenocarcinoma

Y Wang, X Mei, W Song, C Wang, X Qiu - BMC Pulmonary Medicine, 2022 - Springer
Background Lung adenocarcinoma (LUAD) is currently the leading cause of cancer-related
death worldwide. Long noncoding RNAs (lncRNAs) play key roles in tumor occurrence and …