The use of supercontinuum laser sources in biomedical diffuse optics: unlocking the power of multispectral imaging

F Lange, L Giannoni, I Tachtsidis - Applied Sciences, 2021 - mdpi.com
Optical techniques based on diffuse optics have been around for decades now and are
making their way into the day-to-day medical applications. Even though the physics …

Resolution and penetration depth of reflection-mode time-domain near infrared optical tomography using a ToF SPAD camera

J Jiang, M Ackermann, E Russomanno… - Biomedical Optics …, 2022 - opg.optica.org
In a turbid medium such as biological tissue, near-infrared optical tomography (NIROT) can
image the oxygenation, a highly relevant clinical parameter. To be an efficient diagnostic …

Dynamic time domain near-infrared optical tomography based on a SPAD camera

J Jiang, AD Costanzo Mata, S Lindner… - Biomedical optics …, 2020 - opg.optica.org
In many clinical applications it is relevant to observe dynamic changes in oxygenation.
Therefore the ability of dynamic imaging with time domain (TD) near-infrared optical …

2.5 Hz sample rate time-domain near-infrared optical tomography based on SPAD-camera image tissue hemodynamics

J Jiang, AD Costanzo Mata, S Lindner… - Biomedical Optics …, 2021 - opg.optica.org
Time-domain near-infrared optical tomography (TD NIROT) techniques based on diffuse
light were gaining performance over the last years. They are capable of imaging tissue at …

Time-multiplexing approach for fast time-domain near-infrared optical tomography combined with neural-network-enhanced image reconstruction

A Kalyanov, M Ackermann, E Russomanno… - … on Biomedical Optics, 2023 - opg.optica.org
Near-infrared optical tomography (NIROT) is a non-invasive imaging technique based on
diffuse propagation of light in turbid media. It has high sensitivity to tissue oxygenation …

Using spectral derivatives to remove the influence of hair on optical images of the static absorbing properties of tissue-like turbid media

JC Hebden, G Forrester, H Zhang, DM Pacis - Neurophotonics, 2024 - spiedigitallibrary.org
Significance Although measurements of near-infrared light diffusely reflected from the head
and other biological tissues are commonly used to generate images revealing changes in …

Development and validation of robust and cost-effective liquid heterogeneous phantom for time domain near-infrared optical tomography

A Kalyanov, J Jiang, E Russomanno… - Oxygen Transport to …, 2022 - Springer
Diffused light imaging techniques, such as near-infrared optical tomography (NIROT),
require a stable platform for testing and validation that imitates tissue optical properties. The …

In phantom validation of time-domain near-infrared optical tomography pioneer for imaging brain hypoxia and hemorrhage

J Jiang, S Lindner, A Di Costanzo-Mata… - Oxygen Transport to …, 2021 - Springer
The neonatal brain is a vulnerable organ, and lesions due to hemorrhage and/or ischemia
occur frequently in preterm neonates. Even though neuroprotective therapies exist, there is …

Tissue-Mimicking Phantom for Optical Methods

J Jiang - Oxygen Transport to Tissue XLV, 2024 - books.google.com
Tissue mimicking optical phantoms are commonly used to calibrate or validate the
performance of near-infrared spectroscopy or tomography. Human tissue is not only …

SPAD-sensor-based near-infrared imaging and dynamic phantom platform system

T Li, ADC Mata, A Kalyanov… - Optics in Health …, 2023 - spiedigitallibrary.org
We developed a time domain near infrared optical tomography (TD NIROT) system for tissue
imaging. To facilitate its evaluation, we created a dynamic tissue-mimicking phantom …