Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a
broad range of physiological and pathological processes. As a group, these proteins use …

Sarcomas are uncommon malignancies of mesenchymal origin that can arise throughout the
human lifespan, at any part of the body. Surgery remains the optimal treatment modality …

Cancer cells undergoing immunogenic cell death (ICD) can initiate adaptive immune
responses against dead cell‐associated antigens, provided that (1) said antigens are not …

Galectin–Carbohydrate interactions are indispensable to pathogen recognition and immune
response. Galectin-1, a ubiquitously expressed 14-kDa protein with an evolutionarily …

Background Galectin-3 (Gal-3) is a β-galactoside-binding lectin that is highly expressed
within the tumor microenvironment of aggressive cancers and has been suggested to predict …

Nanomedicines are highly promising for cancer therapy due to their minimal side effects.
However, little is known regarding their host immune response, which may limit their clinical …

Galectins are galactoside-binding proteins, exerting numerous functions inside and outside
the cell, particularly conferring adaptation to stress factors. For most of them, aberrant …

Immunotherapy has brought a paradigm shift in the treatment of tumors in recent decades.
However, a significant proportion of patients remain unresponsive, largely due to the …

Changes in cell growth and metabolism are affected by the surrounding environmental
factors to adapt to the cell's most appropriate growth model. However, abnormal cell …