[HTML][HTML] Interoceptive pathways to understand and treat mental health conditions

CL Nord, SN Garfinkel - Trends in Cognitive Sciences, 2022 - cell.com
An increasing recognition that brain and body are dynamically coupled has enriched our
scientific understanding of mental health conditions. Peripheral signals interact centrally to …

Inflammation and post‐traumatic stress disorder

H Hori, Y Kim - Psychiatry and clinical neurosciences, 2019 - Wiley Online Library
While post‐traumatic stress disorder (PTSD) is currently diagnosed based solely on classic
psychological and behavioral symptoms, a growing body of evidence has highlighted a link …

Inflammation in fear-and anxiety-based disorders: PTSD, GAD, and beyond

V Michopoulos, A Powers, CF Gillespie… - …, 2017 - nature.com
The study of inflammation in fear-and anxiety-based disorders has gained interest as
growing literature indicates that pro-inflammatory markers can directly modulate affective …

The role of the immune system in posttraumatic stress disorder

S Katrinli, NCS Oliveira, JC Felger… - Translational …, 2022 - nature.com
Posttraumatic stress disorder (PTSD) develops in a subset of individuals upon exposure to
traumatic stress. In addition to well-defined psychological and behavioral symptoms, some …

Psychological and biological mechanisms linking trauma with cardiovascular disease risk

JA Sumner, S Cleveland, T Chen, JL Gradus - Translational psychiatry, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, and
experiences of psychological trauma have been associated with subsequent CVD onset …

The link between chronic stress and accelerated aging

YE Yegorov, AV Poznyak, NG Nikiforov, IA Sobenin… - Biomedicines, 2020 - mdpi.com
People exposed to chronic stress age rapidly. The telomeres in their cells of all types
shorten faster. Inflammation is another important feature of stress that, along with aging …

Diverse therapeutic developments for post-traumatic stress disorder (PTSD) indicate common mechanisms of memory modulation

SB Raut, PA Marathe, L van Eijk, R Eri… - Pharmacology & …, 2022 - Elsevier
Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …

Neuroprotective effects of angiotensin receptor blockers

S Villapol, JM Saavedra - American journal of hypertension, 2015 - academic.oup.com
Angiotensin II receptor blockers (ARBs, collectively called sartans) are widely used
compounds therapeutically effective in cardiovascular disorders, renal disease, the …

Melatonin as a potential approach to anxiety treatment

K Repova, T Baka, K Krajcirovicova, P Stanko… - International journal of …, 2022 - mdpi.com
Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …

The physiology of fear: reconceptualizing the role of the central amygdala in fear learning

OP Keifer Jr, RC Hurt, KJ Ressler, PJ Marvar - Physiology, 2015 - journals.physiology.org
The historically understood role of the central amygdala (CeA) in fear learning is to serve as
a passive output station for processing and plasticity that occurs elsewhere in the brain …