A comprehensive review on process and engineering aspects of pharmaceutical wet granulation

P Suresh, I Sreedhar, R Vaidhiswaran… - Chemical Engineering …, 2017 - Elsevier
Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …

A review of high shear wet granulation for better process understanding, control and product development

B Liu, J Wang, J Zeng, L Zhao, Y Wang, Y Feng… - Powder Technology, 2021 - Elsevier
High shear wet granulation (HSWG) is considered a complicated and multivariate
pharmaceutical process that is influenced by a large number of variables derived from …

[HTML][HTML] Approaches for improving the flowability of high-protein dairy powders post spray drying–A review

R Hazlett, C Schmidmeier, JA O'Mahony - Powder technology, 2021 - Elsevier
Challenges are commonly encountered in the bulk handling and application of high-protein
dairy powders, and are strongly influenced by their poor flowability. Powder flowability can …

An enhanced constitutive model for crushable granular materials

A Daouadji, PY Hicher - International journal for numerical and …, 2010 - Wiley Online Library
Studies in the past have tried to reproduce the mechanical behaviour of granular materials
by proposing constitutive relations based on a common assumption that model parameters …

Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production–a critical review

A Kumar, KV Gernaey, T De Beer, I Nopens - European Journal of …, 2013 - Elsevier
The manufacturing of pharmaceutical dosage forms, which has traditionally been a batch-
wise process, is now also transformed into a series of continuous operations. Some …

Shaping of porous metal–organic framework granules using mesoporous ρ-alumina as a binder

AH Valekar, KH Cho, UH Lee, JS Lee, JW Yoon… - RSC …, 2017 - pubs.rsc.org
The shaping of metal–organic frameworks (MOFs) on a macroscopic level is a vibrant area
in MOF research. For practical application of MOFs, the fine microcrystalline powder should …

Experimental study of wet granulation in fluidized bed: impact of the binder properties on the granule morphology

P Rajniak, C Mancinelli, RT Chern, F Stepanek… - International journal of …, 2007 - Elsevier
In this work, the effect of the physicochemical properties of aqueous hydroxypropyl-cellulose
(HPC) binder solutions and different pharmaceutical excipients (mannitol and anhydrous …

An analytical treatment to spatially inhomogeneous population balance model

S Hussain, R Kumar - Chaos, Solitons & Fractals, 2024 - Elsevier
In modern liquid–liquid contact components, there is an increasing use of droplet population
balance models. These components include differential and completely mixed contractors …

Mechanics of colloidal supraparticles under compression

J Wang, J Schwenger, A Ströbel, P Feldner, P Herre… - Science …, 2021 - science.org
Colloidal supraparticles are finite, spherical assemblies of many primary particles. To take
advantage of their emergent functionalities, such supraparticles must retain their structural …

A first assessment of the strength of cometary particles collected in-situ by the COSIMA instrument onboard ROSETTA

K Hornung, S Merouane, M Hilchenbach… - Planetary and Space …, 2016 - Elsevier
Soon after the arrival of the ROSETTA spacecraft at Comet 67/P Churyumov-Gerasimenko
the onboard instrument COSIMA (“Cometary Secondary Ion Mass Analyzer”) collected a …