Applications of topological data analysis in oncology

A Bukkuri, N Andor, IK Darcy - Frontiers in artificial intelligence, 2021 - frontiersin.org
The emergence of the information age in the last few decades brought with it an explosion of
biomedical data. But with great power comes great responsibility: there is now a pressing …

The shape of things to come: Topological data analysis and biology, from molecules to organisms

EJ Amézquita, MY Quigley, T Ophelders… - Developmental …, 2020 - Wiley Online Library
Shape is data and data is shape. Biologists are accustomed to thinking about how the shape
of biomolecules, cells, tissues, and organisms arise from the effects of genetics …

Topological data analysis reveals a core gene expression backbone that defines form and function across flowering plants

S Palande, JAM Kaste, MD Roberts, K Segura Abá… - PLoS …, 2023 - journals.plos.org
Since they emerged approximately 125 million years ago, flowering plants have evolved to
dominate the terrestrial landscape and survive in the most inhospitable environments on …

On the effectiveness of persistent homology

R Turkes, GF Montufar, N Otter - Advances in Neural …, 2022 - proceedings.neurips.cc
Persistent homology (PH) is one of the most popular methods in Topological Data Analysis.
Even though PH has been used in many different types of applications, the reasons behind …

Multi-dimensional machine learning approaches for fruit shape phenotyping in strawberry

MJ Feldmann, MA Hardigan, RA Famula… - …, 2020 - academic.oup.com
Background Shape is a critical element of the visual appeal of strawberry fruit and is
influenced by both genetic and non-genetic determinants. Current fruit phenotyping …

The remarkable morphological diversity of leaf shape in sweet potato (Ipomoea batatas): the influence of genetics, environment, and G×E

S Gupta, DM Rosenthal, JR Stinchcombe… - New …, 2020 - Wiley Online Library
Leaf shape, a spectacularly diverse plant trait, varies across taxonomic levels, geography
and in response to environmental differences. However, comprehensive intraspecific …

[HTML][HTML] Mechanics, geometry and genetics of epidermal cell shape regulation: different pieces of the same puzzle

A Sapala, A Runions, RS Smith - Current Opinion in Plant Biology, 2019 - Elsevier
Highlights•Epidermal cells of many plant species have intricate, jigsaw puzzle-like
shapes.•Puzzle cell patterning requires cell-wall partitioning and supracellular coordination.• …

Rootstock effects on scion phenotypes in a 'Chambourcin'experimental vineyard

Z Migicovsky, ZN Harris, LL Klein, M Li… - Horticulture …, 2019 - academic.oup.com
Understanding how root systems modulate shoot system phenotypes is a fundamental
question in plant biology and will be useful in developing resilient agricultural crops. Grafting …

MFCIS: an automatic leaf-based identification pipeline for plant cultivars using deep learning and persistent homology

Y Zhang, J Peng, X Yuan, L Zhang, D Zhu… - Horticulture …, 2021 - academic.oup.com
Recognizing plant cultivars reliably and efficiently can benefit plant breeders in terms of
property rights protection and innovation of germplasm resources. Although leaf image …

Image-based phenotyping for identification of QTL determining fruit shape and size in American cranberry (Vaccinium macrocarpon L.)

L Diaz-Garcia, G Covarrubias-Pazaran, B Schlautman… - PeerJ, 2018 - peerj.com
Image-based phenotyping methodologies are powerful tools to determine quality
parameters for fruit breeders and processors. The fruit size and shape of American cranberry …