L-Arginine in diabetes: clinical and preclinical evidence

I Forzano, R Avvisato, F Varzideh… - Cardiovascular …, 2023 - Springer
Abstract L-Arginine (L-Arg), is a semi-essential amino acid involved in the formation of nitric
oxide. The functional relevance of L-Arg in diabetes mellitus has been evaluated both in …

Pathogenesis and mechanisms of SARS-CoV-2 infection in the intestine, liver, and pancreas

Z Khreefa, MT Barbier, AR Koksal, G Love, L Del Valle - Cells, 2023 - mdpi.com
The novel coronavirus, SARS-CoV-2, rapidly spread worldwide, causing an ongoing global
pandemic. While the respiratory system is the most common site of infection, a significant …

Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single …

M Tosato, R Calvani, A Picca, F Ciciarello, V Galluzzo… - Nutrients, 2022 - mdpi.com
Long COVID, a condition characterized by symptom and/or sign persistence following an
acute COVID-19 episode, is associated with reduced physical performance and endothelial …

Exosomal miR-145 and miR-885 regulate thrombosis in COVID-19

J Gambardella, U Kansakar, C Sardu, V Messina… - … of Pharmacology and …, 2023 - ASPET
We hypothesized that exosomal microRNAs could be implied in the pathogenesis of
thromboembolic complications in coronavirus disease 2019 (COVID-19). We isolated …

Long-COVID syndrome and the cardiovascular system: a review of neurocardiologic effects on multiple systems

NL DePace, J Colombo - Current cardiology reports, 2022 - Springer
Abstract Purpose of Review Long-COVID syndrome is a multi-organ disorder that persists
beyond 12 weeks post-acute SARS-CoV-2 infection (COVID-19). Here, we provide a …

Nutraceuticals and dietary supplements for older adults with long COVID-19

M Tosato, F Ciciarello, MB Zazzara… - Clinics in geriatric …, 2022 - geriatric.theclinics.com
SARS-CoV-2 infection affects multiple organs owing to the ubiquitous distribution of its target
receptor ACE-2. 1 Increasing interest has been paid to the postacute phase of COVID-19 …

Effect of a nutritional support system to increase survival and reduce mortality in patients with COVID-19 in stage III and comorbidities: a blinded randomized controlled …

F Leal-Martínez, L Abarca-Bernal… - International journal of …, 2022 - mdpi.com
The COVID-19 evolution depends on immunological capacity. The global hospital mortality
rate is 15–20%, but in México it is 46%. There are several therapeutic protocols, however …

[HTML][HTML] Interplay between comorbidities and long COVID: challenges and multidisciplinary approaches

R Ashmawy, EA Hammouda, YA El-Maradny… - Biomolecules, 2024 - mdpi.com
Long COVID, a name often given to the persistent symptoms following acute SARS-CoV-2
infection, poses a multifaceted challenge for health. This review explores the intrinsic …

L-arginine: its role in human physiology, in some diseases and mainly in viral multiplication as a narrative literature review

MC Pedrazini, EF Martinez, VAB dos Santos… - Future Journal of …, 2024 - Springer
Background L-arginine (Arg) is an amino acid that contributes to several aspects of human
biochemistry. Individuals with malnutrition and certain physical conditions could benefit from …

[HTML][HTML] Beneficial effects of L-Arginine in patients hospitalized for COVID-19: new insights from a randomized clinical trial

V Trimarco, R Izzo, A Lombardi, A Coppola… - Pharmacological …, 2023 - Elsevier
We have recently demonstrated in a double-blind randomized trial the beneficial effects of L-
Arginine in patients hospitalized for COVID-19. We hypothesize that one of the mechanisms …