Fundamentals of methanogenic pathways that are key to the biomethanation of complex biomass

JG Ferry - Current opinion in biotechnology, 2011 - Elsevier
The conversion of biomass to CH4 (biomethanation) involves an anaerobic microbial food
chain composed of at least three metabolic groups of which the first two decompose the …

ATP synthase evolution on a cross-braced dated tree of life

TA Mahendrarajah, ERR Moody, D Schrempf… - Nature …, 2023 - nature.com
The timing of early cellular evolution, from the divergence of Archaea and Bacteria to the
origin of eukaryotes, is poorly constrained. The ATP synthase complex is thought to have …

Genetic techniques for the archaea

JA Farkas, JW Picking… - Annual review of genetics, 2013 - annualreviews.org
Genetic techniques for the Archaea have undergone a rapid expansion in complexity,
resulting in increased exploration of the role of Archaea in the environment and detailed …

Genome-scale metabolic reconstruction and hypothesis testing in the methanogenic archaeon Methanosarcina acetivorans C2A

MN Benedict, MC Gonnerman, WW Metcalf… - Journal of …, 2012 - Am Soc Microbiol
Methanosarcina acetivorans strain C2A is a marine methanogenic archaeon notable for its
substrate utilization, genetic tractability, and novel energy conservation mechanisms. To …

Characterization of the N-ATPase, a distinct, laterally transferred Na+-translocating form of the bacterial F-type membrane ATPase

DV Dibrova, MY Galperin, AY Mulkidjanian - Bioinformatics, 2010 - academic.oup.com
An analysis of the distribution of the Na+-translocating ATPases/ATP synthases among
microbial genomes identified an atypical form of the F1Fo-type ATPase that is present in the …

Overview of the genetic tools in the Archaea

H Atomi, T Imanaka, T Fukui - Frontiers in microbiology, 2012 - frontiersin.org
This section provides an overview of the genetic systems developed in the Archaea. Genetic
manipulation is possible in many members of the halophiles, methanogens, Sulfolobus, and …

Electron transport in acetate-grown Methanosarcina acetivorans

M Wang, JF Tomb, JG Ferry - BMC microbiology, 2011 - Springer
Background Acetate is the major source of methane in nature. The majority of investigations
have focused on acetotrophic methanogens for which energy-conserving electron transport …

The dual role of a multi‐heme cytochrome in methanogenesis: MmcA is important for energy conservation and carbon metabolism in Methanosarcina acetivorans

BE Downing, D Gupta, DD Nayak - Molecular Microbiology, 2023 - Wiley Online Library
Methanogenic archaea belonging to the Order Methanosarcinales conserve energy using
an electron transport chain (ETC). In the genetically tractable strain Methanosarcina …

Carbon-dependent control of electron transfer and central carbon pathway genes for methane biosynthesis in the Archaean, Methanosarcina acetivorans strain C2A

L Rohlin, RP Gunsalus - Bmc Microbiology, 2010 - Springer
Abstract Background The archaeon, Methanosarcina acetivorans strain C2A forms methane,
a potent greenhouse gas, from a variety of one-carbon substrates and acetate. Whereas the …

ATP synthase ecto-α-subunit: a novel therapeutic target for breast cancer

J Pan, LC Sun, YF Tao, Z Zhou, XL Du, L Peng… - Journal of Translational …, 2011 - Springer
Background Treatment failure for breast cancer is frequently due to lymph node metastasis
and invasion to neighboring organs. The aim of the present study was to investigate …