Therapeutic potential of melatonin in targeting molecular pathways of organ fibrosis

A Hosseinzadeh, MH Pourhanifeh, S Amiri… - Pharmacological …, 2024 - Springer
Fibrosis, the excessive deposition of fibrous connective tissue in an organ in response to
injury, is a pathological condition affecting many individuals worldwide. Fibrosis causes the …

[HTML][HTML] Effect of sacubitril/valsartan on the hypertensive heart in continuous light-induced and lactacystin-induced pre-hypertension: Interactions with the renin …

F Simko, P Stanko, K Repova, T Baka… - Biomedicine & …, 2024 - Elsevier
This study investigated whether sacubitril/valsartan or valsartan are able to prevent left
ventricular (LV) fibrotic remodelling and dysfunction in two experimental models of pre …

Revealing the sequence characteristics and molecular mechanisms of ACE inhibitory peptides by comprehensive characterization of 160,000 tetrapeptides

M Ma, Y Feng, Y Miao, Q Shen, S Tang, J Dong… - Foods, 2023 - mdpi.com
Chronic diseases, such as hypertension, cause great harm to human health. Conventional
drugs have promising therapeutic effects, but also cause significant side effects. Food …

[PDF][PDF] Ivabradine curbs isoproterenol-induced kidney fibrosis.

T Baka, P Stanko, K Repova, S Aziriova… - General Physiology & …, 2023 - researchgate.net
This study investigated whether chronic isoproterenol administration could induce kidney
alterations and whether ivabradine, a heart rate (HR)-reducing substance exerting …