Highlights•PDI is an important oxidase, reductase, isomerase and molecular
chaperone.•PDI expression is up-regulated in select types of cancers.•Silencing PDI results …

During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Thrombosis, or blood clot formation, and its sequelae remain a leading cause of morbidity
and mortality, and recurrent thrombosis is common despite current optimal therapy. Protein …

Protein disulfide isomerase (PDI), is a member of the thioredoxin superfamily of redox
proteins. PDI has three catalytic activities including, thiol-disulfide oxireductase, disulfide …

Highlights•Overview of copper complexes as potent anticancer chemotherapeutic
agents.•Copper complexes are endogenously biocompatible and exhibit reduced side …

Protein disulfide isomerase (PDI), an endoplasmic reticulum chaperone protein, catalyzes
disulfide bond breakage, formation, and rearrangement. The effect of PDI inhibition on …

Ever since antibiotics were used to help humanity battle infectious diseases,
microorganisms straight away fought back. Antibiotic resistance mechanisms indeed provide …

Bacitracin is a macrocyclic peptide antibiotic that is widely used as a topical treatment for
infections caused by gram-positive bacteria. Mechanistically, bacitracin targets bacteria by …

Introduction Airway epithelial cells have been described to release extracellular vesicles
(EVs) with pathological properties when exposed to cigarette smoke extract (CSE). As CSE …