Minocycline as a prospective therapeutic agent for cancer and non-cancer diseases: a scoping review

A Rezaei, A Moqadami, M Khalaj-Kondori - … -Schmiedeberg's Archives of …, 2024 - Springer
Minocycline is an FDA-approved secondary-generation tetracycline antibiotic. It is a
synthetic antibiotic having many biological effects, such as antioxidant, anti-inflammatory …

Effects of Bu Shen Hua Zhuo formula on the LPS/TLR4 pathway and gut microbiota in rats with letrozole-induced polycystic ovary syndrome

Y Wang, H Xiao, Y Liu, Q Tong, Y Yu, B Qi… - Frontiers in …, 2022 - frontiersin.org
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
gynecology. Traditional Chinese medicine (TCM) is widely used for the treatment of PCOS in …

The Antidiabetic Mechanisms of Hesperidin: Hesperidin Nanocarriers as Promising Therapeutic Options for Diabetes

F Kaviani, I Baratpour, S Ghasemi - Current Molecular Medicine, 2024 - benthamdirect.com
A natural flavonoid with exceptional medicinal capabilities, hesperidin, has shown
encouraging results in the treatment of diabetes. Thoughts are still being held on the …

Ameliorating effects of adropin on letrozole‐induced polycystic ovary syndrome via regulating steroidogenesis and the microbiota inflammatory axis in rats

FH Rizk, AA El Saadany, AM Elshamy… - The Journal of …, 2024 - Wiley Online Library
Growing evidence supports the role of gut microbiota in chronic inflammation, insulin
resistance (IR) and sex hormone production in polycystic ovary syndrome (PCOS). Adropin …

Modulatory effects of R10 fraction of garlic (Allium sativum L.) on hormonal levels, T cell polarization, and fertility-related genes in mice model of polycystic ovarian …

S Falahatian, R Haddad, N Pakravan - Journal of Ovarian Research, 2022 - Springer
Polycystic ovary syndrome (PCOS) is an inflammatory endocrine-metabolic disorder related
to reproductive system characterized by polycystic ovarian morphology, androgen excess …

Isorhamnetin inhibits inflammatory response to alleviate DHEA-induced polycystic ovary syndrome in rats

F Yu, Y Xue, Y Zhao, L Zhang, X He… - Gynecological …, 2023 - Taylor & Francis
Objective To explore the role of isorhamnetin on polycystic ovary syndrome (PCOS) in rats.
Methods Sprague Dawley (SD) rats were subcutaneously injected with …

[HTML][HTML] The significant improvement in ovarian PCOS syndrome using hydralazine and alendronate aromatase inhibitor FDA-approved drugs in Wistar rat models

S Kavousipour, F Koohnavard, B Shahbazi… - Biomedicine & …, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. The
aim of this study was to investigate the therapeutic potential of vitamin C, glutamine …

Therapeutic potential of 3-acetyl coumarin against polycystic ovarian syndrome induced by letrozole using female rats

S Shahbaz, A Sharif, B Akhtar, A Mobashar… - Naunyn-Schmiedeberg's …, 2024 - Springer
Polycystic ovarian syndrome is a heterogeneous endocrine disorder characterized by
ovarian cysts, anovulation, endocrine variations, which includes oligo-amenorrhea along …

[HTML][HTML] Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

M Kian, E Hosseini, T Abdizadeh, T Langaee… - EXCLI …, 2022 - ncbi.nlm.nih.gov
Polycystic ovary syndrome (PCOS) is the most common cause of women's infertility. Some
inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to …

[HTML][HTML] Exploring the Association of Biochemical Characterization and Genetic Determinants of TNF-α, CXCR2, and CCR5 Delta 32 Mutation with Predisposition to …

KS Almasoudi, E Hussain, R Almotairi, T Bhat… - Life, 2024 - mdpi.com
PCOS is a heterogeneous, multifactorial endocrine disorder with a complex
pathophysiology. It is a globally rising infertility disorder that affects a large percentage of …