Maternal immunisation: collaborating with mother nature

A Marchant, M Sadarangani, M Garand… - The lancet infectious …, 2017 - thelancet.com
Maternal immunisation has the potential to substantially reduce morbidity and mortality from
infectious diseases after birth. The success of tetanus, influenza, and pertussis immunisation …

The immunological balance between host and parasite in malaria

K Deroost, TT Pham, G Opdenakker… - FEMS microbiology …, 2016 - academic.oup.com
Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Shared transcriptional profiles of atypical B cells suggest common drivers of expansion and function in malaria, HIV, and autoimmunity

P Holla, B Dizon, AA Ambegaonkar, N Rogel… - Science …, 2021 - science.org
Chronic infectious diseases have a substantial impact on the human B cell compartment
including a notable expansion of B cells here termed atypical B cells (ABCs). Using …

FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure

RT Sullivan, CC Kim, MF Fontana, ME Feeney… - PLoS …, 2015 - journals.plos.org
Exposure to Plasmodium falciparum is associated with circulating “atypical” memory B cells
(atMBCs), which appear similar to dysfunctional B cells found in HIV-infected individuals …

The immunology of Plasmodium vivax malaria

LR Antonelli, C Junqueira, JM Vinetz… - Immunological …, 2020 - Wiley Online Library
Plasmodium vivax infection, the predominant cause of malaria in Asia and Latin America,
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …

Immunity to malaria in an era of declining malaria transmission

FJI Fowkes, P Boeuf, JG Beeson - Parasitology, 2016 - cambridge.org
With increasing malaria control and goals of malaria elimination, many endemic areas are
transitioning from high-to-low-to-no malaria transmission. Reductions in transmission will …

CXCL13 and CCL11 serum levels and lymphoma and disease activity in primary Sjögren's syndrome

G Nocturne, R Seror, O Fogel, R Belkhir… - Arthritis & …, 2015 - Wiley Online Library
Objective Non‐Hodgkin's lymphoma (NHL) is a severe complication of primary Sjögren's
syndrome (SS). Ectopic germinal centers (GCs) in the salivary glands are predictors of the …

Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS, S/AS01E vaccination in African children

I Ubillos, A Ayestaran, AJ Nhabomba, D Dosoo… - BMC medicine, 2018 - Springer
Abstract Background The RTS, S/AS01E vaccine provides partial protection against malaria
in African children, but immune responses have only been partially characterized and do not …

T follicular helper cells regulate the activation of B lymphocytes and antibody production during Plasmodium vivax infection

MM Figueiredo, PAC Costa, SQ Diniz… - PLoS …, 2017 - journals.plos.org
Although the importance of humoral immunity to malaria has been established, factors that
control antibody production are poorly understood. Follicular helper T cells (Tfh cells) are …

[HTML][HTML] Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling

LG Gardinassi, M Arévalo-Herrera, S Herrera… - Redox biology, 2018 - Elsevier
Almost invariably, humans become ill during primary infections with malaria parasites which
is a pathology associated with oxidative stress and perturbations in metabolism. Importantly …