The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
Chorioamnionitis and neonatal outcomes
Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth.
Chorioamnionitis can affect almost every organ of the developing fetus. Multiple microbes …
Chorioamnionitis can affect almost every organ of the developing fetus. Multiple microbes …
Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics
Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
The prenatal gut microbiome: are we colonized with bacteria in utero?
RW Walker, JC Clemente, I Peter, RJF Loos - Pediatric obesity, 2017 - Wiley Online Library
The colonization of the gut with microbes in early life is critical to the developing newborn
immune system, metabolic function and potentially future health. Maternal microbes are …
immune system, metabolic function and potentially future health. Maternal microbes are …
Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes
Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …
The placental membrane microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis
Background Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality and
is not uncommonly associated with chorioamnionitis. We recently have demonstrated that …
is not uncommonly associated with chorioamnionitis. We recently have demonstrated that …
[HTML][HTML] Endometrial microbiota—new player in town
I Moreno, JM Franasiak - Fertility and sterility, 2017 - Elsevier
Detection of bacteria with molecular techniques has enabled the study of low biomass
microbiomes in tissues and organs previously considered sterile, such as the endometrium …
microbiomes in tissues and organs previously considered sterile, such as the endometrium …
The frequency and type of placental histologic lesions in term pregnancies with normal outcome
Objective To determine the frequency and type of histopathologic lesions in placentas
delivered by women with a normal pregnancy outcome. Methods This retrospective cohort …
delivered by women with a normal pregnancy outcome. Methods This retrospective cohort …
[HTML][HTML] Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques
Introduction: The objectives of this study were: 1) to determine the amniotic fluid (AF)
microbiology of patients with the diagnosis of clinical chorioamnionitis at term using both …
microbiology of patients with the diagnosis of clinical chorioamnionitis at term using both …