Human (visceral) obesity is associated with alterations hypothalamus–pituitary–adrenal
(HPA) axis functioning. It is however not completely clear whether the HPA axis is causally …

Glucocorticoids (GCs) are steroid hormones, naturally produced by activation of the
hypothalamic-pituitary-adrenal (HPA) axis, that mediate the immune and metabolic systems …

Chronic exposure to glucocorticoid hormones, resulting from either drug treatment or
Cushing's syndrome, results in insulin resistance, central obesity, and symptoms similar to …

Protocatechuic acid (PCA), the natural phenolic antioxidant, reportedly exhibited
hypoglycemic and insulin-like effects. Recent studies have reported its cardioprotective …

This study investigated whether exercise training could prevent the negative side effects of
dexamethasone. Rats underwent a training period and were either submitted to a running …

Several clinical and experimental lines of evidence have highlighted the detrimental effects
of visceral adipose tissue excess on cardiometabolic parameters. Besides, recent findings …

Objective—To determine the effects of dexamethasone treatment on selected components of
insulin signaling and glucose metabolism in skeletal muscle obtained from horses before …

This study investigated how proteins of the insulin signaling cascade could modulate insulin
resistance after dexamethasone (Dexa) treatment and aerobic training. Rats were …

Aims/hypothesis Obesity and type 2 diabetes are among the most serious health
pathologies worldwide. Stress has been proposed as a factor contributing to the …

Reasons for performing the study Dexamethasone is an anti‐inflammatory drug commonly
used in equine medicine. Insulin sensitivity decreases with prolonged dexamethasone …