Recent advances in high-throughput technologies have led to the emergence of systems
biology as a holistic science to achieve more precise modeling of complex diseases. Many …

Next-generation sequencing has made major strides in the past decade. Studies based on
large sequencing data sets are growing in number, and public archives for raw sequencing …

High-throughput bioinformatic analyses increasingly rely on pipeline frameworks to process
sequence and metadata. Modern implementations of these frameworks differ on three key …

Abstract The Eukaryotic Pathogen Genomics Database Resource (EuPathDB,
http://eupathdb. org) is a collection of databases covering 170+ eukaryotic pathogens …

Long noncoding RNAs (lncRNAs) are emerging as a class of important regulators
participating in various biological functions and disease processes. With the widespread …

Biomedical research has become a digital data–intensive endeavor, relying on secure and
scalable computing, storage, and network infrastructure, which has traditionally been …

Comparative genomics is the comparison of genetic information within and across
organisms to understand the evolution, structure, and function of genes, proteins, and non …

Viruses cause significant yield and quality losses in a wide variety of cultivated crops.
Hence, the detection and identification of viruses is a crucial facet of successful crop …

Background Analyzing high throughput genomics data is a complex and compute intensive
task, generally requiring numerous software tools and large reference data sets, tied …

Fighting infections and developing novel drugs and vaccines requires advanced knowledge
of pathogen's biology. Readily accessible genomic, functional genomic, and population data …