Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: useful nutraceuticals?

V Martínez, A Iriondo De-Hond, F Borrelli… - International Journal of …, 2020 - mdpi.com
Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used
for different purposes, like the production of fibers, the production of oil from the seeds, and …

Momordica charantia polysaccharides ameliorate oxidative stress, inflammation, and apoptosis in ethanol-induced gastritis in mucosa through NF-kB signaling …

M Raish, A Ahmad, MA Ansari, KM Alkharfy… - International Journal of …, 2018 - Elsevier
This study investigated the therapeutic role of polysaccharides from M. charantia and their
mechanism of action against ethanol-induced gastric ulcers in rats. Their effects were …

Drug discovery strategies for modulating oxidative stress in gastrointestinal disorders

T Mousavi, N Hadizadeh, S Nikfar… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction Due to the ever-growing incidence of gastrointestinal disorders accompanied by
substantial economic impact, it is of great importance to manage these conditions globally …

AdipoRon, an orally active, synthetic agonist of AdipoR1 and AdipoR2 receptors has gastroprotective effect in experimentally induced gastric ulcers in mice

H Zatorski, M Salaga, M Zielińska, K Majchrzak… - Molecules, 2021 - mdpi.com
Introduction: Adiponectin is a hormone secreted by adipocytes, which exhibits insulin-
sensitizing and anti-inflammatory properties and acts through adiponectin receptors …

Research on the structural characteristics of a novel Chinese Iron Yam polysaccharide and its gastroprotection mechanism against ethanol-induced gastric mucosal …

M Guo, H Yu, M Meng, C Wang - Food & function, 2020 - pubs.rsc.org
In this study, a triple-helix Chinese Iron Yam polysaccharide (CIYP) with a molecular weight
of 1.67× 103 kDa was obtained. The CIYP was extracted with deionized water followed by …

Sonchus oleraceus L. Promotes Gastroprotection in Rodents via Antioxidant, Anti‐Inflammatory, and Antisecretory Activities

CAD Vecchia, G Locateli, PZ Serpa… - Evidence‐Based …, 2022 - Wiley Online Library
Sonchus oleraceus L. is an edible and medicinal plant used to treat stomachache and
gastric ailments around the world. Thus, this study aimed to determine the gastroprotective …

Development of a gastroprotector from Algrizea minor essential oil complexed with β-Cyclodextrin

PHE Fernandes, CSC Alves… - Journal of Drug Delivery …, 2024 - Elsevier
Algrizea minor, a member of the Myrtaceae family, is found in the Cerrado and Caatinga
biomes. Essential oils (EO) are highly volatile, prompting the need to minimize volatilization …

Efficiency and Mechanism Evaluation of Magnolia officinalis Water Extract in Preventing Gastric Ulcer

KP Shen, CD Chang, MH Hsieh… - Evidence‐Based …, 2023 - Wiley Online Library
In this study we aimed at demonstrating the ability of Magnolia officinalis water extract to
ameliorate gastric ulcers in in vitro and in vivo experiments. The gastric mucosa epithelial …

Gastroprotective mechanisms

CAA de Lima, RS de Lima, JB de Souza… - Peptic Ulcer Disease …, 2022 - books.google.com
Gastric ulcer (GU), a common type of peptic ulcer, results from an imbalance in the action of
protective and aggressive agents. Gastroprotective mechanisms are mucus layer, gastric …

High activity of endogenous opioid system protects against gastric damage development in mouse models of gastric mucosal injury

H Zatorski, M Salaga, M Zielińska, A Wasilewski… - Pharmacological …, 2019 - Elsevier
Background Gastric mucosal injury appears when acid and pepsin production,
simultaneously with inadequate mucosal response, overwhelms protective mechanism in …