Osteochondroma is the most common benign bone tumor and usually occurs in the
metaphyseal region of the long bones. This tumor takes the form of a cartilage-capped bony …

The solitary osteochondroma, a common pediatric bone tumor, is a cartilage-capped
exostosis. Hereditary multiple exostosis is an autosomal dominant disorder manifested by …

Hereditary multiple exostoses (HME, OMIM 133700, 133701) results from mutations in EXT1
and EXT2, genes encoding the copolymerase responsible for heparan sulfate (HS) …

Osteochondromas are bone protuberances surrounded by a cartilage layer. They generally
affect the extremities of the longbones in an immature skeleton and deform them. They …

Osteochondromas represent the most common primary bone tumours; they reportedly
represent 20-50% of all benign bone tumours and 10-15% of all bone tumours. Malignant …

The material presented at or in any Vindico Medical Education continuing education activity
does not necessarily reflect the views and opinions of Vindico Medical Education or …

Objective To analyze the results of annual screening using whole-body magnetic resonance
imaging (WBMRI) in patients with multiple hereditary exostoses (MHE) and …

Simple Summary Chondrosarcomas are a very heterogeneous group of cartilage-forming
tumors that comprise approximately one-third of all malignant bone tumors. The World …

Multiple Hereditary Exostoses (MHE) syndrome is caused by haploinsufficiency in Golgi-
associated heparan sulfate polymerases EXT1 or EXT2 and is characterized by formation of …

Background The most serious complication of hereditary multiple exostoses (HME) is
chondrosarcoma transformation. Numerous authors have suggested that screening might …