Harnessing genomic information for livestock improvement

M Georges, C Charlier, B Hayes - Nature Reviews Genetics, 2019 - nature.com
The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …

Role of fatty acids in milk fat and the influence of selected factors on their variability—a review

O Hanuš, E Samková, L Křížová, L Hasoňová, R Kala - Molecules, 2018 - mdpi.com
Fatty acids (FAs) of milk fat are considered to be important nutritional components of the
diets of a significant portion of the human population and substantially affect human health …

Within-breed and multi-breed GWAS on imputed whole-genome sequence variants reveal candidate mutations affecting milk protein composition in dairy cattle

MP Sanchez, A Govignon-Gion, P Croiseau… - Genetics Selection …, 2017 - Springer
Background Genome-wide association studies (GWAS) were performed at the sequence
level to identify candidate mutations that affect the expression of six major milk proteins in …

Sequence-based Association Analysis Reveals an MGST1 eQTL with Pleiotropic Effects on Bovine Milk Composition

MD Littlejohn, K Tiplady, TA Fink, K Lehnert… - Scientific reports, 2016 - nature.com
The mammary gland is a prolific lipogenic organ, synthesising copious amounts of
triglycerides for secretion into milk. The fat content of milk varies widely both between and …

Confirmed effects of candidate variants for milk production, udder health, and udder morphology in dairy cattle

T Tribout, P Croiseau, R Lefebvre, A Barbat… - Genetics Selection …, 2020 - Springer
Background Over the last years, genome-wide association studies (GWAS) based on
imputed whole-genome sequences (WGS) have been used to detect quantitative trait loci …

A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle

YL Lee, H Takeda, G Costa Monteiro Moreira… - PLoS …, 2021 - journals.plos.org
Clinical mastitis (CM) is an inflammatory disease occurring in the mammary glands of
lactating cows. CM is under genetic control, and a prominent CM resistance QTL located on …

CNV discovery for milk composition traits in dairy cattle using whole genome resequencing

Y Gao, J Jiang, S Yang, Y Hou, GE Liu, S Zhang… - BMC genomics, 2017 - Springer
Abstract Background Copy number variations (CNVs) are important and widely distributed in
the genome. CNV detection opens a new avenue for exploring genes associated with …

[HTML][HTML] Comparison of the genetic characteristics of directly measured and Fourier-transform mid-infrared-predicted bovine milk fatty acids and proteins

KM Tiplady, TJ Lopdell, RG Sherlock, TJJ Johnson… - Journal of Dairy …, 2022 - Elsevier
Fourier-transform mid-infrared (FT-MIR) spectroscopy is a high-throughput and inexpensive
methodology used to evaluate concentrations of fat and protein in dairy cattle milk samples …

[HTML][HTML] Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle

S Nayeri, M Sargolzaei, MK Abo-Ismail, S Miller… - Journal of dairy …, 2017 - Elsevier
Female fertility in Holstein cattle can decline when intense genetic selection is placed on
milk production. One approach to improving fertility is to identify the genomic regions and …

Genetic markers associated with milk production traits in dairy cattle

Y Ma, MZ Khan, J Xiao, GM Alugongo, X Chen, T Chen… - Agriculture, 2021 - mdpi.com
Increasing milk production is one of the key concerns in animal production. Traditional
breeding has gotten limited achievement in the improvement of milk production because of …