Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …

GABA A receptors are the major inhibitory transmitter receptors in the brain. They are ligand-
gated chloride channels and the site of action of benzodiazepines, barbiturates, neuroactive …

Cancer is one of the leading causes of death worldwide and a major global health problem.
In recent decades, the rates of both mortality and morbidity of cancer have rapidly increased …

The flavonoids, baicalin, and its aglycone baicalein possess multi-fold therapeutic properties
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …

Abstract Baicalein (5, 6, 7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one) is a flavonoid
compound derived from the roots of Scutellaria baicalensis. It has historically been used in …

Cancer, being a multifactorial disease has diverse presentation in different subgroups which
is mainly attributed to heterogenous presentation of tumor cells. This cancer cell …

Mitochondria play an essential role in cell survival by providing energy, calcium buffering,
and regulating apoptosis. A growing body of evidence shows that mitochondrial dysfunction …

Simple Summary Cancer is a multifactorial disease characterized by excessive cell
proliferation in a specific organ. The most common treatments include chemotherapy …

Scutellaria baicalensis (Huangqin in Chinese) is a major traditional Chinese medicine
(TCM) herb, which has a long history of use in the treatment of a variety of symptoms …

Baicalein, a flavonoid and aglycon hydrolyzed from baicalin, has anticancer properties in
several human carcinomas, but its molecular mechanisms of action remain unclear. Here …