Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect

I San-Millán, GA Brooks - Carcinogenesis, 2017 - academic.oup.com
Herein, we use lessons learned in exercise physiology and metabolism to propose that
augmented lactate production ('lactagenesis'), initiated by gene mutations, is the reason and …

Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology

S Laye, A Nadjar, C Joffre, RP Bazinet… - Pharmacological …, 2018 - Elsevier
Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

The role of extracellular vesicles in COVID-19 virus infection

M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …

Increased miR‐124‐3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer …

S Huang, X Ge, J Yu, Z Han, Z Yin, Y Li… - The FASEB …, 2018 - Wiley Online Library
Neuronal inflammation is the characteristic pathologic change of acute neurologic
impairment and chronic traumatic encephalopathy after traumatic brain injury (TBI) …

Extracellular vesicles round off communication in the nervous system

V Budnik, C Ruiz-Cañada, F Wendler - Nature Reviews Neuroscience, 2016 - nature.com
Functional neural competence and integrity require interactive exchanges among sensory
and motor neurons, interneurons and glial cells. Recent studies have attributed some of the …

[HTML][HTML] Cell-to-cell communication by extracellular vesicles: focus on microglia

RC Paolicelli, G Bergamini, L Rajendran - Neuroscience, 2019 - Elsevier
Extracellular vesicles, including exosomes and microvesicles, are small, nano-to-micrometer
vesicles that are released from cells. While initially observed in immune cells and …

Neuroinflammation and depression: microglia activation, extracellular microvesicles and microRNA dysregulation

D Brites, A Fernandes - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Patients with chronic inflammation are often associated with the emergence of depression
symptoms, while diagnosed depressed patients show increased levels of circulating …

Extracellular vesicles: biology and emerging therapeutic opportunities

S El Andaloussi, I Mäger, XO Breakefield… - Nature reviews Drug …, 2013 - nature.com
Within the past decade, extracellular vesicles have emerged as important mediators of
intercellular communication, being involved in the transmission of biological signals …

Biomarkers for parkinsonian disorders in CNS-originating EVs: promise and challenges

S Dutta, S Hornung, HB Taha, G Bitan - Acta neuropathologica, 2023 - Springer
Extracellular vesicles (EVs), including exosomes, microvesicles, and oncosomes, are nano-
sized particles enclosed by a lipid bilayer. EVs are released by virtually all eukaryotic cells …