Covering: bacterial genome sequences to 2005 and post-genomic literature to June 2006 A
total of 223 complete bacterial genomes are analyzed, with 281 citations, for the presence of …

Phylogenetic hypotheses using whole genome sequences have the potential for
unprecedented accuracy, yet a failure to understand issues associated with discovery bias …

Conventional classification of the species in the family Mycoplasmataceae is mainly based
on phenotypic criteria, which are complicated, can be difficult to measure, and have the …

Another concern about identifying human genes on the basis of sequence alone had to do
with the fragmentation of genes in 'higher'eukaryotes, whereby coding information is …

Increasing emergence of antibiotic-resistant pathogenic microorganisms is one of the
biggest challenges for biomedical research and drug development. Traditional drug …

The modular cell design principle is formulated to devise modular (chassis) cells. These
cells can be assembled with exchangeable production modules in a plug-and-play fashion …

Mycoplasma bovis is an economically important pathogen of the cattle industry worldwide,
and there is an urgent need for a more effective vaccine to control the diseases caused by …

The emerging antibiotic resistant bacteria and their abilities for rapid evolution have pushed
the need to explore alternative antibiotics less prone to drug resistance. In this study, we …

Background The creation of successful health policy and location of resources increasingly
relies on evidence-based decision-making. The development of intuitive, accessible tools to …

The tyrosyl free radical in protein R2-2 of class Ib ribonucleotide reductase (RNR) from
Mycobacterium tuberculosis is essential for the enzymatic activity and has an EPR spectrum …