Major review: Molecular genetics of primary open-angle glaucoma
Y Liu, RR Allingham - Experimental eye research, 2017 - Elsevier
Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
The vast complexity of primary open angle glaucoma: disease genes, risks, molecular mechanisms and pathobiology
SF Janssen, TGMF Gorgels, WD Ramdas… - Progress in retinal and …, 2013 - Elsevier
Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics
H Springelkamp, AI Iglesias, A Mishra… - Human molecular …, 2017 - academic.oup.com
Primary open-angle glaucoma (POAG), the most common optic neuropathy, is a heritable
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …
An updated review on the genetics of primary open angle glaucoma
K Abu-Amero, AA Kondkar, KV Chalam - International journal of …, 2015 - mdpi.com
Epidemiological studies suggest that by 2020 the prevalence of primary open angle
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …
Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images
Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is
used to diagnose and manage ophthalmic diseases including glaucoma. We present the …
used to diagnose and manage ophthalmic diseases including glaucoma. We present the …
A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma
SS Verma, HV Gudiseva, VRM Chavali, RJ Salowe… - Cell, 2024 - cell.com
Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness
worldwide, disproportionately affects individuals of African ancestry. We conducted a …
worldwide, disproportionately affects individuals of African ancestry. We conducted a …
[HTML][HTML] Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry
Purpose.: Multiple genes have been associated with primary open angle glaucoma (POAG)
in Caucasian populations. We now examine the association of these loci in populations of …
in Caucasian populations. We now examine the association of these loci in populations of …
Cis-expression quantitative trait loci mapping reveals replicable associations with heroin addiction in OPRM1
DB Hancock, JL Levy, NC Gaddis, C Glasheen… - Biological …, 2015 - Elsevier
Background No opioid receptor, mu 1 (OPRM1) gene polymorphisms, including the
functional single nucleotide polymorphism (SNP) rs1799971, have been conclusively …
functional single nucleotide polymorphism (SNP) rs1799971, have been conclusively …
Ophthalmic epidemiology in europe: the “European eye epidemiology”(E3) consortium
C Delcourt, JF Korobelnik, GHS Buitendijk… - European journal of …, 2016 - Springer
Abstract The European Eye Epidemiology (E3) consortium is a recently formed consortium
of 29 groups from 12 European countries. It already comprises 21 population-based studies …
of 29 groups from 12 European countries. It already comprises 21 population-based studies …
Genetic variants associated with different risks for high tension glaucoma and normal tension glaucoma in a Chinese population
Y Chen, G Hughes, X Chen, S Qian… - … & visual science, 2015 - iovs.arvojournals.org
Purpose.: We investigated the association of genetic factors with primary open angle
glaucoma (POAG), including high tension glaucoma (HTG) and normal tension glaucoma …
glaucoma (POAG), including high tension glaucoma (HTG) and normal tension glaucoma …