Complex injectable drug products (CIDPs) have often been developed to modulate the
pharmacokinetics along with efficacy for therapeutic agents used for remediation of chronic …

The aim of this paper was to explore tablet design options for FDM 3D printing for
simultaneous tailoring of drug release and dose. The drug, griseofulvin (GF), the polymer …

Purpose: To review in vitro testing and simulation platforms that are in current use to predict
in vivo performances of generic products as well as other situations to provide evidence for …

Personalized medicine aims to effectively and efficiently provide customized drugs that cater
to diverse populations, which is a significant yet challenging task. Recently, the integration of …

Filaments loaded with griseofulvin (GF), a model poorly water-soluble drug, were prepared
and used for 3D printing via fused deposition modeling (FDM). GF was selected due to its …

The aim of this work was to develop a mucoadhesive iontophoretic patch for anesthetic
delivery in the buccal epithelium. The patch was comprised of three different layers, namely …

The use of the USP IV apparatus (flow-through cell) has gained acceptance in recent years
due to its versatility and ability to discriminate due to its hydrodynamic conditions. Therefore …

Introduction The calculation of the 90% confidence interval of f 2 based on the bootstrap
methodology has been proposed and accepted by the main regulatory authorities when the …

For some postapproval changes, the manufacturer has to demonstrate that the dissolution
profile of the drug product before the change is statistically equivalent to the dissolution …

Quantitative evaluation of drug dissolution characteristics based on mathematical models is
essential to understand and predict a particular drug release profile. In this study, model …