Antimicrobial peptides towards clinical application: Delivery and formulation

C Wang, T Hong, P Cui, J Wang, J Xia - Advanced drug delivery reviews, 2021 - Elsevier
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …

Advances of peptides for antibacterial applications

Y Yan, Y Li, Z Zhang, X Wang, Y Niu, S Zhang… - Colloids and Surfaces B …, 2021 - Elsevier
In the past few decades, peptide antibacterial products with unique antibacterial
mechanisms have attracted widespread interest. They can effectively reduce the probability …

Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides

I Greco, N Molchanova, E Holmedal, H Jenssen… - Scientific reports, 2020 - nature.com
The use of non-standard toxicity models is a hurdle in the early development of antimicrobial
peptides towards clinical applications. Herein we report an extensive in vitro and in vivo …

Rejuvenated photodynamic therapy for bacterial infections

Q Jia, Q Song, P Li, W Huang - Advanced healthcare materials, 2019 - Wiley Online Library
The emergence of multidrug resistant bacterial strains has hastened the exploration of
advanced microbicides and antibacterial techniques. Photodynamic antibacterial therapy …

Small bioactive peptides for biomaterials design and therapeutics

IW Hamley - Chemical reviews, 2017 - ACS Publications
This review is aimed to provide a concise yet extensive survey of key short bioactive peptide
sequences for a range of applications ranging from biomaterials development to peptides …

Enzyme mimicry for combating bacteria and biofilms

Z Chen, Z Wang, J Ren, X Qu - Accounts of Chemical Research, 2018 - ACS Publications
Conspectus Bacterial infection continues to be a growing global health problem with the
most widely accepted treatment paradigms restricted to antibiotics. However, antibiotics …

Multicomponent peptide assemblies

DM Raymond, BL Nilsson - Chemical Society Reviews, 2018 - pubs.rsc.org
Self-assembled peptide nanostructures have been increasingly exploited as functional
materials for applications in biomedicine and energy. The emergent properties of these …

Antimicrobial peptides: from design to clinical application

C Zhang, M Yang - Antibiotics, 2022 - mdpi.com
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …

[HTML][HTML] Two-dimensional nanomaterials beyond graphene for antibacterial applications: current progress and future perspectives

L Mei, S Zhu, W Yin, C Chen, G Nie, Z Gu, Y Zhao - Theranostics, 2020 - ncbi.nlm.nih.gov
The marked augment of drug-resistance to traditional antibiotics underlines the crying need
for novel replaceable antibacterials. Research advances have revealed the considerable …

Poly (pentahydropyrimidine)‐Based Hybrid Hydrogel with Synergistic Antibacterial and Pro‐Angiogenic Ability for the Therapy of Diabetic Foot Ulcers

W Li, H Chen, J Cai, M Wang, X Zhou… - Advanced Functional …, 2023 - Wiley Online Library
Bacterial infection and impaired angiogenesis make the treatment of diabetic foot ulcers
(DFU) extremely challenging. Cationic polymers are expected to treat infected wounds due …