Circulating tumor cells: biology and clinical significance

D Lin, L Shen, M Luo, K Zhang, J Li, Q Yang… - Signal transduction and …, 2021 - nature.com
Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

Liquid biopsy in pancreatic cancer: Are we ready to apply it in the clinical practice?

V Heredia-Soto, N Rodríguez-Salas, J Feliu - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the tumors with the
highest mortality, for which survival has hardly changed in the last 40 years. This high …

Photonic technologies for liquid biopsies: recent advances and open research challenges

F Dell'Olio, J Su, T Huser, V Sottile… - Laser & photonics …, 2021 - Wiley Online Library
The recent development of sophisticated techniques capable of detecting extremely low
concentrations of circulating tumor biomarkers in accessible body fluids, such as blood or …

Microfluidic platforms for single cell analysis: applications in cellular manipulation and optical biosensing

S Kumari, U Saha, M Bose, D Murugan, V Pachauri… - Chemosensors, 2023 - mdpi.com
Cellular heterogeneity of any tissue or organ makes it challenging to identify and study the
impact and the treatment of any disease. In this context, analysis of cells at an individual …

A Microfluidic Chip for Efficient Circulating Tumor Cells Enrichment, Screening, and Single‐Cell RNA Sequencing

F Shi, F Jia, Z Wei, Y Ma, Z Fang, W Zhang, Z Hu - Proteomics, 2021 - Wiley Online Library
Single‐cell RNA sequencing on circulating tumor cells (CTCs) proves useful to study
mechanisms of tumor heterogeneity, metastasis, and drug resistance. Currently, single‐cell …

Rapid detection of EGFR mutation in CTCs based on a double spiral microfluidic chip and the real-time RPA method

WM Li, XD Ren, YZ Jiang, N Su, BW Li, XG Sun… - Analytical and …, 2023 - Springer
Circulating tumor cells (CTCs) are cells shed from primary or metastatic tumors and spread
into the peripheral bloodstream. Mutation detection in CTCs can reveal vital genetic …

[HTML][HTML] Powerful quantifiers for cancer transcriptomics

DA Iacobas - World journal of clinical oncology, 2020 - ncbi.nlm.nih.gov
Every day, investigators find a new link between a form of cancer and a particular alteration
in the sequence or/and expression level of a key gene, awarding this gene the title of …

MXene-based nucleic acid biosensors for agricultural and food systems

W Wang, S Gunasekaran - Biosensors, 2022 - mdpi.com
MXene is a two-dimensional (2D) nanomaterial that exhibits several superior properties
suitable for fabricating biosensors. Likewise, the nucleic acid (NA) in oligomerization forms …

[HTML][HTML] Advanced single-cell and spatial analysis with high-multiplex characterization of circulating tumor cells and tumor tissue in prostate cancer: Unveiling …

L Bonstingl, M Zinnegger… - Biomarker …, 2024 - biomarkerres.biomedcentral.com
Metastatic prostate cancer is a highly heterogeneous and dynamic disease and practicable
tools for patient stratification and resistance monitoring are urgently needed. Liquid biopsy …