Approximately half of all lesions of the ovary in childhood are neoplastic, yet only a small
fraction of neoplastic lesions contain malignant elements. Overall, malignancies of the ovary …

DICER1 tumor predisposition (DICER1) is characterized by an increased risk for
pleuropulmonary blastoma (PPB), pulmonary cysts, thyroid gland neoplasia (multinodular …

Abstract Study Objective To report on the clinical characteristics and outcome of pediatric
patients with juvenile granulosa cell tumor (JGCT) of the ovary. Design, Setting, Participants …

We analyzed 72 patients with ovarian sex cord–stromal tumors (OSCST) registered at the
German Pediatric Tumor Registry in Kiel over a 20-year period. Juvenile granulosa cell …

Background Ovarian sex‐cord stromal tumors (SCST) are rare in childhood and include a
variety of neoplasms with different clinical features and biologic behavior. Aim of the …

Surgical staging should always be performed. It includes peritoneal samplings (peritoneal
washing, multiple peritoneal biopsies, omental biopsy and biopsy of any suspicious area) …

Germ cell tumors include a group of tumors that are highly heterogeneous regarding their
clinical and histologic appearance. Altogether they comprise approximately 2–3% of …

Pediatric ovarian and testicular sex cord-stromal tumors are distinct from germ cell
neoplasms and may present with palpable mass or signs of hormone production. Both may …

The presentation of adnexal masses in childhood differs from that in adult women. Children
may present with poorly localized symptoms or precocious puberty. Ovarian cysts occur …

To identify the appropriate management we review the current literature on the diagnostic
and different surgical procedures to which the patients affected by Sertoli–Leyding cell …