The dopamine transporter has a crucial role in regulation of dopaminergic
neurotransmission by uptake of dopamine into neurons and contributes to the abuse …

The escalating prevalence of new psychoactive substances (NPSs) poses a significant
public health challenge, evidenced by the vast chemical diversity, with over 500 substances …

The presynaptic serotonin transporter (SERT) clears extracellular serotonin following
vesicular release to ensure temporal and spatial regulation of serotonergic signalling and …

Cocaine is a highly addictive psychostimulant drug of abuse that constitutes an ongoing
public health threat. Emerging research is revealing that numerous peripheral effects of this …

Changes in the molecular structure of synthetic cathinones has led to an increase in the
number of novel emerging drugs in the illicit drug market at an unprecedented rate …

Many psychoactive compounds have been shown to primarily interact with high-affinity and
low-capacity solute carrier 6 (SLC6) monoamine transporters for norepinephrine (NET; …

The dopamine transporter (DAT) is an integral member of the dopaminergic system and is
responsible for the release and reuptake of dopamine from the synaptic space into the …

Abstract 1‐(2, 3‐Dihydro‐1H‐inden‐5‐yl)‐2‐(piperidin‐1‐yl) pentan‐1‐one (3, 4‐Pr‐PipVP),
a novel synthetic cathinone (SCat), was first identified in 2022 in Germany. The product was …

Structures of the dopamine transporter point to ways to target addiction and disease Skip to
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Methylenedioxymethamphetamine (MDMA,'ecstasy') is re‐emerging in clinical settings as a
candidate for the treatment of specific neuropsychiatric disorders (eg post‐traumatic stress …