The key objective of JAMA is “To promote the science and art of medicine and the
betterment of the public health”; similar objectives and mission statements are supported by …

Importance Enzyme-inducing antiseizure medications (eiASMs) have been hypothesized to
be associated with long-term risks of cardiovascular disease. Objective To quantify and …

Background Electronic medical records (EMRs) contain large amounts of rich clinical
information. Developing EMR-based case definitions, also known as EMR phenotyping, is …

Objective To describe hospital admissions associated with SARS-CoV-2 infection in children
and adolescents. Design Cohort study of 3.2 million first ascertained SARS-CoV-2 infections …

Progress of machine learning in critical care has been difficult to track, in part due to
absence of public benchmarks. Other fields of research (such as computer vision and …

Importance Both epilepsy and enzyme-inducing antiseizure medications (eiASMs) having
varying reports of an association with increased risks for osteoporosis. Objective To quantify …

Objective The incidence of late‐onset epilepsy (LOE) is rising, and these patients may use
an excess of health care resources. This study aimed to measure pre‐/post‐diagnostic …

Objective To use clinically informed machine learning to derive prediction models for early
and late premature death in epilepsy. Methods This was a population‐based primary care …

Objective This study was undertaken to identify clusters of adult onset epilepsy with distinct
comorbidities and risks of early and late death. Methods This was a retrospective open …

Background and objectives Late-onset epilepsy is a heterogenous entity associated with
specific aetiologies and an elevated risk of premature mortality. Specific multimorbid …